Keppra and Triatec drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keppra (levetiracetam) and Triatec (ramipril). Common drug interactions include acute pulmonary oedema among females and agranulocytosis among males.
The phase IV clinical study analyzes what interactions people have when they take Keppra and Triatec. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Keppra?
Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.
What is Triatec?
Triatec has active ingredients of ramipril. eHealthMe is studying from 4,133 Triatec users. Check the latest studies of Triatec.
34 people who take Keppra and Triatec together, and have interactions are studied.

What are the common drug interactions of Keppra and Triatec, by gender? *:
female:
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Thrombocytopenia (decrease of platelets in blood)
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Arthralgia (joint pain)
- Cerebral haematoma (collection of blood in brain)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Large intestinal haemorrhage (bleeding in large intestine)
- Multiple injuries
male:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Neutropenia (an abnormally low number of neutrophils)
- Fatigue (feeling of tiredness)
- General physical health deterioration (weak health status)
- Hyperkalaemia (damage to or disease of the kidney)
- Leukopenia (less number of white blood cells in blood)
- Malaise (a feeling of general discomfort or uneasiness)
- Muscular weakness (muscle weakness)
- Oedema peripheral (superficial swelling)
- Somnolence (a state of near-sleep, a strong desire for sleep)
What are the common drug interactions of Keppra and Triatec, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Leukopenia (less number of white blood cells in blood)
- Neutropenia (an abnormally low number of neutrophils)
- Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Pyrexia (fever)
- Vertigo
50-59:
- Hepatocellular injury (liver injury)
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Hepatitis acute
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Cerebral haematoma (collection of blood in brain)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Inflammation
- Lactic acidosis (low ph in body tissues)
60+:
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Arthralgia (joint pain)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dysarthria (speech disorder)
- Embolic stroke (stroke due to obstruction due to an embolus)
- Endocarditis (inflammation in heart muscle)
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Large intestinal haemorrhage (bleeding in large intestine)
- Multiple injuries
What are the existing conditions these people have? *
- High Blood Pressure: 8 people, 23.53%
- Infection: 3 people, 8.82%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 8.82%
- Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 5.88%
- Pain: 2 people, 5.88%
- Lymphoma (cancer that begins in immune system cells): 2 people, 5.88%
- Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 2 people, 5.88%
- High Blood Cholesterol: 2 people, 5.88%
- Enlarged Prostate: 2 people, 5.88%
- Dyslipidaemia (abnormal amount of lipids): 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Keppra and Triatec?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Keppra and Triatec:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Keppra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Triatec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keppra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Triatec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on levetiracetam and ramipril (the active ingredients of Keppra and Triatec, respectively), and Keppra and Triatec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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