Keppra and Viread drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keppra (levetiracetam) and Viread (tenofovir disoproxil fumarate). Common drug interactions include acute respiratory distress syndrome among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Keppra and Viread. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

What is Viread?

Viread has active ingredients of tenofovir disoproxil fumarate. It is often used in hepatitis b. eHealthMe is studying from 51,542 Viread users. Check the latest studies of Viread.

On Jul, 13, 2026

77 people who take Keppra and Viread together, and have interactions are studied.

What are the common drug interactions of Keppra and Viread, by gender? *:

female:

Acute respiratory distress syndrome
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dry eye (lack of adequate tears)
Faecaloma (hard mass of fecal matter)
Flatulence (flatus expelled through the anus)
Histiocytosis haematophagic
Osteonecrosis (death of bone)
Pneumococcal sepsis (pneumococcal sepsis is a serious medical condition where bacteria, specifically streptococcus pneumoniae)

male:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Photosensitivity reaction
Rash erythematous (redness of the skin)
Renal impairment (severely reduced kidney function)
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Tooth loss
Upper limb fracture

What are the common drug interactions of Keppra and Viread, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Oedema (fluid collection in tissue)
Acute respiratory distress syndrome
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Emotional distress
Histiocytosis haematophagic
Hypertension (high blood pressure)

30-39:

Anxiety
Back pain
Bone density decreased
Bone loss
Depression
Mobility decreased (ability to move is reduced)
Multiple fractures
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

40-49:

Anxiety
Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Emotional distress
Pain
Anaemia (lack of blood)
Blood creatinine increased
Renal impairment (severely reduced kidney function)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

Intervertebral disc degeneration (spinal disc degeneration)
Lung disorder (lung disease)
Multiple fractures
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Neuropathy peripheral (surface nerve damage)
Osteopenia (a condition where bone mineral density is lower than normal)
Renal impairment (severely reduced kidney function)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Spinal cord compression
Spinal fracture (fracture in one of vertebrae)

60+:

Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Pain
Anxiety
Chronic kidney disease
Emotional distress
Neoplasm malignant (cancer tumour)
Pancreas infection
Renal disorder (kidney disease)
Diarrhoea
Spinal compression fracture (fracture due to spinal compression on bone)

What are the existing conditions these people have? *

Hiv Infection: 45 people, 58.44%
Pain: 16 people, 20.78%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 12 people, 15.58%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 9 people, 11.69%
Stress And Anxiety: 6 people, 7.79%
Gastritis (inflammation of stomach): 6 people, 7.79%
Otitis (ear infection): 5 people, 6.49%
High Blood Cholesterol: 5 people, 6.49%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 5 people, 6.49%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

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