Ketoconazole and Abacavir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Abacavir (abacavir sulfate). Common drug interactions include angioneurotic oedema among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Abacavir. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Abacavir?

Abacavir has active ingredients of abacavir sulfate. It is often used in hiv infection. eHealthMe is studying from 8,306 Abacavir users. Check the latest studies of Abacavir.

On Jul, 10, 2026

30 people who take Ketoconazole and Abacavir together, and have interactions are studied.

Ketoconazole and Abacavir drug interactions.

What are the common drug interactions of Ketoconazole and Abacavir, by gender? *:

female:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Coma (state of unconsciousness lasting more than six hours)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dyspnoea (difficult or laboured respiration)
Face oedema (swelling of face)
Mottled skin (a condition in which the skin becomes discoloured in irregular patches)
Pulse absent
Pyrexia (fever)
Rash erythematous (redness of the skin)

male:

Chronic kidney disease
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Protein urine present
Quality of life decreased
Bone disorder
Renal tubular necrosis (death of kidney tubules)
Anaemia (lack of blood)
Bone density decreased
Bone metabolism disorder

What are the common drug interactions of Ketoconazole and Abacavir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Overdose

10-19:

n/a

20-29:

Hepatitis (inflammation of the liver)

30-39:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Coma (state of unconsciousness lasting more than six hours)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dyspnoea (difficult or laboured respiration)
Face oedema (swelling of face)
Mottled skin (a condition in which the skin becomes discoloured in irregular patches)
Pain
Pulse absent
Pyrexia (fever)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Decreased activity
Emotional distress
Impaired work ability
Pain
Quality of life decreased

50-59:

Pain
Renal failure (kidney dysfunction)
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Osteoporosis (bones weak and more likely to break)
Renal tubular necrosis (death of kidney tubules)
Bone density decreased
Bone metabolism disorder
Decreased activity
Impaired work ability
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

60+:

Anaemia (lack of blood)
Chronic kidney disease
Hepatitis c
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Pain: 2 people, 6.67%
Infection: 2 people, 6.67%
High Blood Pressure: 2 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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