Ketoconazole and Bextra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Bextra (valdecoxib). Common drug interactions include bone disorder among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Bextra. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

On Jul, 07, 2026

41 people who take Ketoconazole and Bextra together, and have interactions are studied.

Ketoconazole and Bextra drug interactions.

What are the common drug interactions of Ketoconazole and Bextra, by gender? *:

female:

Bone disorder
Chest pain
Death
Dental caries
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Headache (pain in head)
Inflammation
Mouth ulceration (mouth ulcers)
Purulent discharge (discharge that contains pus)
Weight decreased

male:

Anaemia (lack of blood)
Anxiety
Osteonecrosis of jaw (death of bone of jaw)
Inflammation
Tooth abscess (pus formation in tooth)
Cardiac failure congestive
Cellulitis (infection under the skin)
Chest pain
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Necrosis (the death of body tissue)

What are the common drug interactions of Ketoconazole and Bextra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Adrenal neoplasm (abnormal growth of adrenal gland)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Biliary cyst

50-59:

Abdominal pain
Adrenal neoplasm (abnormal growth of adrenal gland)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Aortic valve disease
Aortic valve incompetence
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Biliary cyst
Bladder hypertrophy (bladder overgrowth- increase in cell size)

60+:

Headache (pain in head)
Atelectasis (partial or complete collapse of the lung)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Anaemia (lack of blood)
Anxiety
Bile duct stone
Blood cholesterol increased
Bone fragmentation

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 21 people, 51.22%
Trismus (reduced opening of the jaws): 16 people, 39.02%
Prostate Cancer: 8 people, 19.51%
Depression: 7 people, 17.07%
Bone Pain: 7 people, 17.07%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 14.63%
Insomnia (sleeplessness): 5 people, 12.20%
Infection: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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