Ketoconazole and Codeine sulfate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Codeine sulfate (codeine sulfate). Common drug interactions include memory impairment among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Codeine sulfate. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Ketoconazole?
Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.
What is Codeine sulfate?
Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.
26 people who take Ketoconazole and Codeine sulfate together, and have interactions are studied.

What are the common drug interactions of Ketoconazole and Codeine Sulfate, by gender? *:
female:
- Memory impairment
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Oedema peripheral (superficial swelling)
- Overweight
- Skin infection
- Spider vein (small dilated blood vessels near the surface of the skin)
- Apathy
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
male:
- Death
- Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
- Abdominal pain upper
- Abscess jaw (tooth abscess or root abscess)
- Actinomycosis (infection that causes sores, or abscesses)
- Acute sinusitis
- Alanine aminotransferase increased
- Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
- Anaemia (lack of blood)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
What are the common drug interactions of Ketoconazole and Codeine Sulfate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Device related infection
- Drug ineffective
- Dry eye (lack of adequate tears)
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Eye pain
- Fatigue (feeling of tiredness)
- Folliculitis (infection of hair root)
50-59:
- Acute sinusitis
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Death
- Pneumonia
- Pyrexia (fever)
60+:
- Abdominal pain upper
- Abscess jaw (tooth abscess or root abscess)
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Back disorder
- Bile duct stone
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Blood calcium decreased
- Blood creatinine decreased
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 38.46%
- Hiv Infection: 3 people, 11.54%
- High Blood Cholesterol: 3 people, 11.54%
- Breast Cancer Metastatic: 3 people, 11.54%
- Haemorrhage (bleeding): 3 people, 11.54%
- Aortic Valve Incompetence: 3 people, 11.54%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 7.69%
- Leukaemia (blood or bone marrow cancer): 2 people, 7.69%
- Tooth Disorder (tooth disease): 2 people, 7.69%
- Muscle Spasms (muscle contraction): 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Ketoconazole and Codeine sulfate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ketoconazole (16,014 reports)
- Codeine sulfate (4,510 reports)
Browse all drug interactions of Ketoconazole and Codeine sulfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ketoconazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Codeine sulfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ketoconazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Codeine sulfate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ketoconazole and codeine sulfate (the active ingredients of Ketoconazole and Codeine sulfate, respectively), and Ketoconazole and Codeine sulfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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