Ketoconazole and Dronabinol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoconazole (ketoconazole) and Dronabinol (dronabinol). Common drug interactions include implant site erosion among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoconazole and Dronabinol. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoconazole?

Ketoconazole has active ingredients of ketoconazole. It is often used in fungal infection. eHealthMe is studying from 16,014 Ketoconazole users. Check the latest studies of Ketoconazole.

What is Dronabinol?

Dronabinol has active ingredients of dronabinol. eHealthMe is studying from 5,453 Dronabinol users. Check the latest studies of Dronabinol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

50 people who take Ketoconazole and Dronabinol together, and have interactions are studied.

Ketoconazole and Dronabinol drug interactions.

What are the common drug interactions of Ketoconazole and Dronabinol, by gender? *:

female:

  1. Implant site erosion
  2. Implant site infection
  3. Multiple fractures
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Decreased immune responsiveness
  6. Urinary tract infection
  7. Back pain
  8. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  9. Breast pain
  10. Chapped lips (cracking, fissuring, and peeling of the skin f lip)

male:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Multiple fractures
  4. Gait disturbance
  5. Ankle fracture
  6. Foot fracture
  7. Tooth loss
  8. Asthenia (weakness)
  9. Hand fracture
  10. Muscle atrophy (a decrease in the mass of the muscle)

What are the common drug interactions of Ketoconazole and Dronabinol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Foot fracture
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Ankle fracture
  4. Anxiety
  5. Bone density decreased
  6. Depression
  7. Emotional distress
  8. Gait disturbance
  9. Hand fracture
  10. Muscle atrophy (a decrease in the mass of the muscle)

30-39:

  1. Anxiety
  2. Depression
  3. Emotional distress
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Pain
  6. Bone density decreased
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Back pain
  9. Blood urine present
  10. Decreased activity

40-49:

  1. Urticaria (rash of round, red welts on the skin that itch intensely)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Emotional distress
  5. Pain
  6. Bone density decreased
  7. Osteoporosis (bones weak and more likely to break)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Bone loss

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Bone density decreased
  6. Renal failure (kidney dysfunction)
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Multiple fractures
  9. Osteoporosis (bones weak and more likely to break)
  10. Chronic kidney disease

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Bone loss
  4. Breast pain
  5. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  6. Chronic kidney disease
  7. Fatigue (feeling of tiredness)
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Haematuria (presence of blood in urine)
  10. Hospitalisation

What are the existing conditions these people have? *

  1. Hiv Infection: 33 people, 66.00%
  2. Pain: 10 people, 20.00%
  3. Hypersensitivity: 9 people, 18.00%
  4. Nausea (feeling of having an urge to vomit): 9 people, 18.00%
  5. High Blood Pressure: 8 people, 16.00%
  6. Insomnia (sleeplessness): 7 people, 14.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.00%
  8. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 10.00%
  9. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 10.00%
  10. Bacterial Infection: 5 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ketoconazole and Dronabinol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ketoconazole and Dronabinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ketoconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dronabinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketoconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dronabinol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ketoconazole and dronabinol (the active ingredients of Ketoconazole and Dronabinol, respectively), and Ketoconazole and Dronabinol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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