Keytruda and Meropenem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keytruda (pembrolizumab) and Meropenem (meropenem). Common drug interactions include aspartate aminotransferase increased among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Keytruda and Meropenem. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Keytruda?

Keytruda has active ingredients of pembrolizumab. It is often used in renal cell carcinoma. eHealthMe is studying from 57,404 Keytruda users. Check the latest studies of Keytruda.

What is Meropenem?

Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.

On Jul, 10, 2026

78 people who take Keytruda and Meropenem together, and have interactions are studied.

Keytruda and Meropenem drug interactions.

What are the common drug interactions of Keytruda and Meropenem, by gender? *:

female:

Aspartate aminotransferase increased
Blood pressure decreased
C-reactive protein increased
Chills (felling of cold)
Dysgeusia (disorder of the sense of taste)
Eye disorder
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypokalaemia (low potassium)
Infection
Liver disorder (liver diseases)

male:

Interstitial lung disease
Pyrexia (fever)
Fungal infection
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Liver disorder (liver diseases)
Platelet count decreased
Small intestinal haemorrhage (bleeding from small intestine)
Febrile neutropenia (fever with reduced white blood cells)
Hepatic enzyme increased
Decreased appetite

What are the common drug interactions of Keytruda and Meropenem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Death
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Malignant neoplasm progression (cancer tumour came back)

40-49:

Febrile neutropenia (fever with reduced white blood cells)
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
Septic shock (shock due to blood infection)
Visual acuity reduced (reduced clearness of vision)
Pyrexia (fever)
Anaemia (lack of blood)
Back pain
Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)

50-59:

Malignant neoplasm progression (cancer tumour came back)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Carbohydrate antigen 19-9 increased
Carcinoembryonic antigen increased
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hypertension (high blood pressure)
Hyperthyroidism (over activity of the thyroid gland)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Muscular weakness (muscle weakness)

60+:

Interstitial lung disease
Pyrexia (fever)
Bacterial infection
Blood beta-d-glucan increased
C-reactive protein increased
Fungal infection
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Liver disorder (liver diseases)
Small intestinal haemorrhage (bleeding from small intestine)
Febrile neutropenia (fever with reduced white blood cells)

What are the existing conditions these people have? *

Interstitial Lung Disease: 17 people, 21.79%
Fever: 15 people, 19.23%
Lung Cancer - Non-Small Cell (lung cancer): 13 people, 16.67%
High Blood Pressure: 11 people, 14.10%
Type 2 Diabetes: 10 people, 12.82%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 9 people, 11.54%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 11.54%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 6 people, 7.69%
Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 6 people, 7.69%
Pain: 6 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Keytruda and Meropenem?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously