Leukine and Spinal osteoarthritis - a phase IV clinical study of FDA data

Summary:

Spinal osteoarthritis is reported as a side effect among people who take Leukine (sargramostim), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Taxotere, and have Osteoporosis.

The phase IV clinical study analyzes which people have Spinal osteoarthritis when taking Leukine. It is created by eHealthMe based on reports of 2,173 people who have side effects when taking Leukine from the FDA, and is updated regularly.

What is Leukine?

Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.

What is Spinal osteoarthritis?

Spinal osteoarthritis (joint cartilage loss in spine) is found to be associated with 1,422 drugs and 1,124 conditions by eHealthMe. Check the latest studies of Spinal osteoarthritis.

On Jul, 10, 2026

2,173 people reported to have side effects when taking Leukine.
Among them, 22 people (1.01%) have Spinal osteoarthritis.

Could Leukine cause Spinal osteoarthritis?

Among these 22 people:

How long have people been on Leukine when they have Spinal osteoarthritis? *

What is the gender of people who have Spinal osteoarthritis when taking Leukine? *

female: 9.09 %
male: 90.91 %

What is the age of people who have Spinal osteoarthritis when taking Leukine? *

What are other drugs people take besides Leukine? *

What are other side effects people have besides Spinal osteoarthritis? *

Pain: 22 people, 100.00%
High Blood Pressure: 22 people, 100.00%
Osteopenia (a condition where bone mineral density is lower than normal): 22 people, 100.00%
Weight Decreased: 21 people, 95.45%
Back Pain: 21 people, 95.45%
Bone Disorder: 21 people, 95.45%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 21 people, 95.45%
Gallstones (stone formation by bile component): 21 people, 95.45%
Abdominal Pain: 21 people, 95.45%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 20 people, 90.91%

What are the existing conditions these people have? *

Prostate Cancer: 13 people, 59.09%
Osteoporosis (bones weak and more likely to break): 13 people, 59.09%
High Blood Cholesterol: 12 people, 54.55%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 9.09%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 4.55%
Pain In Extremity: 1 person, 4.55%
Pain: 1 person, 4.55%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 4.55%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 1 person, 4.55%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Leukine and have Spinal osteoarthritis?

- Check whether Spinal osteoarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Leukine:

Leukine (2,188 reports)

Browse all side effects of Leukine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal osteoarthritis:

Spinal osteoarthritis (1,422 drugs)

Browse all the conditions that are associated with Spinal osteoarthritis:

Spinal osteoarthritis (1,124 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sargramostim (the active ingredients of Leukine) and Leukine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.