Kineret and Hydrocortisone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kineret (anakinra) and Hydrocortisone (hydrocortisone). Common drug interactions include acute respiratory distress syndrome among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Kineret and Hydrocortisone. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Kineret?

Kineret has active ingredients of anakinra. It is often used in rheumatoid arthritis. eHealthMe is studying from 11,120 Kineret users. Check the latest studies of Kineret.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

On Jul, 25, 2026

44 people who take Kineret and Hydrocortisone together, and have interactions are studied.

Kineret and Hydrocortisone drug interactions.

What are the common drug interactions of Kineret and Hydrocortisone, by gender? *:

female:

Acute respiratory distress syndrome
Affect lability (emotional incontinence)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anxiety
Cerebrovascular disorder (disease of brain)
Chills (felling of cold)
Cholecystitis acute (rapid infection of gallbladder)
Clostridial infection (infectious conditions by clostridium bacteria)
Cough
Crying

male:

Renal failure (kidney dysfunction)
Arm amputation
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chronic gastritis (long lasting infection of stomach lining)
Fluid intake reduced
Haematochezia (passage of stools containing blood)
Inflammatory marker increased
Proctitis (inflammation of the rectum and anus)
Streptococcal infection
Urinary tract infection

What are the common drug interactions of Kineret and Hydrocortisone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Adrenal suppression (suppression of cortisol secretion by the adrenal glands)
Antinuclear antibody positive
Psoriasis (immune-mediated disease that affects the skin)
Abdominal pain upper
Erythema (redness of the skin)
Injection site erythema (redness at injection site)
Injection site pain
Injection site pruritus (severe itching at injection site)
Mass
Pain

10-19:

n/a

20-29:

Abdominal pain upper
Chest pain
Dyspepsia (indigestion)
Headache (pain in head)
Injection site discomfort
Injection site erythema (redness at injection site)
Injection site mass
Injection site pain
Injection site rash
Injection site swelling

30-39:

Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Nail infection
Nephrolithiasis (calculi in the kidneys)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Purpura (purplish discoloration of the skin)
Tendon pain
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection
Vomiting

40-49:

Injection site reaction
Pyrexia (fever)

50-59:

Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Renal failure (kidney dysfunction)
Arm amputation
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Diarrhoea
Streptococcal sepsis (whole body inflammation by streptococcal)
Vomiting
Amyloidosis (a tumour within which amyloid is produced)
Gangrene (body tissue dies)

60+:

Acute respiratory distress syndrome
Cerebrovascular disorder (disease of brain)
Neutropenia (an abnormally low number of neutrophils)
Oliguria (not enough urine)
Osteoporotic fracture (fracture due to weak bone)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Renal failure (kidney dysfunction)
Respiratory disorder (respiratory disease)
Septic shock (shock due to blood infection)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

What are the existing conditions these people have? *

Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 5 people, 11.36%
Humoral Immune Defect (impairment of humoral immunity): 5 people, 11.36%
Immunodeficiency Common Variable: 4 people, 9.09%
Heart Attack: 4 people, 9.09%
Fever: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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