Kionex and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kionex (sodium polystyrene sulfonate) and Nexium (esomeprazole magnesium). Common drug interactions include blister among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Kionex and Nexium. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Kionex?

Kionex has active ingredients of sodium polystyrene sulfonate. eHealthMe is studying from 478 Kionex users. Check the latest studies of Kionex.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.

On Aug, 02, 2026

82 people who take Kionex and Nexium together, and have interactions are studied.

What are the common drug interactions of Kionex and Nexium, by gender? *:

female:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood culture positive
Bone cyst
Bone density decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Catheter site infection (infection at the site of insertion)
Cervix carcinoma (cancer of cervix)
Chills (felling of cold)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Depression
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Post-traumatic stress disorder
Renal tubular necrosis (death of kidney tubules)
Secondary hyperthyroidism
Type 1 diabetes mellitus
Renal hypertension (high blood pressure caused by the kidneys hormonal response)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Kionex and Nexium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease

40-49:

Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal injury (kidney injury)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Death
Nephropathy (damage to or disease of a kidney)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Blood culture positive
Bone cyst

50-59:

Renal failure (kidney dysfunction)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypervolaemia (abnormally increased volume of blood)
Death
Depression
Post-traumatic stress disorder
Renal injury (kidney injury)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Renal tubular necrosis (death of kidney tubules)
Type 1 diabetes mellitus
Asthenia (weakness)
Nausea (feeling of having an urge to vomit)
Pneumonia
Renal disorder (kidney disease)
Weight decreased

What are the existing conditions these people have? *

High Blood Cholesterol: 34 people, 41.46%
High Blood Pressure: 34 people, 41.46%
Pain: 32 people, 39.02%
Diabetes: 31 people, 37.80%
Stress And Anxiety: 24 people, 29.27%
Hyperkalemia (damage to or disease of the kidney): 24 people, 29.27%
Indigestion: 24 people, 29.27%
Depression: 19 people, 23.17%
Infection: 18 people, 21.95%
Fungal Infection: 17 people, 20.73%

* Approximation only. Some reports may have incomplete information.

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