Kionex and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kionex (sodium polystyrene sulfonate) and Prilosec (omeprazole). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Kionex and Prilosec. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Kionex?

Kionex has active ingredients of sodium polystyrene sulfonate. eHealthMe is studying from 478 Kionex users. Check the latest studies of Kionex.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

On Jul, 17, 2026

63 people who take Kionex and Prilosec together, and have interactions are studied.

What are the common drug interactions of Kionex and Prilosec, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Renal disorder (kidney disease)
Nephrogenic anaemia (anaemia due to kidney disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Death
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypervolaemia (abnormally increased volume of blood)
Diarrhoea

male:

Chronic kidney disease
Renal injury (kidney injury)
Fatigue (feeling of tiredness)
Hyperkalaemia (damage to or disease of the kidney)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Renal hypertension (high blood pressure caused by the kidneys hormonal response)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Cardiac disorder

What are the common drug interactions of Kionex and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Asthenia (weakness)

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypervolaemia (abnormally increased volume of blood)
Death
Depression
Post-traumatic stress disorder
Renal injury (kidney injury)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Pruritus (severe itching of the skin)
Renal hypertension (high blood pressure caused by the kidneys hormonal response)
Abdominal distension
Chest pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Pain: 28 people, 44.44%
High Blood Cholesterol: 19 people, 30.16%
Stress And Anxiety: 18 people, 28.57%
High Blood Pressure: 18 people, 28.57%
Hyperkalemia (damage to or disease of the kidney): 18 people, 28.57%
Diabetes: 15 people, 23.81%
Indigestion: 13 people, 20.63%
Blood Pressure Abnormal: 10 people, 15.87%
Fungal Infection: 10 people, 15.87%
Multiple Allergies (allergy to multiple agents): 9 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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