Klor-con m20 and Opsumit drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Klor-con m20 (potassium chloride) and Opsumit (macitentan). Common drug interactions include infusion site swelling among females and cough among males.
The phase IV clinical study analyzes what interactions people have when they take Klor-con m20 and Opsumit. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.
What is Klor-con m20?
Klor-con m20 has active ingredients of potassium chloride. It is often used in hypokalemia. eHealthMe is studying from 2,411 Klor-con m20 users. Check the latest studies of Klor-con m20.
What is Opsumit?
Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.
42 people who take Klor-con m20 and Opsumit together, and have interactions are studied.

What are the common drug interactions of Klor-Con M20 and Opsumit, by gender? *:
female:
- Infusion site swelling
- Infusion site warmth
- Insomnia (sleeplessness)
- Joint swelling
- Liver disorder (liver diseases)
- Malaise (a feeling of general discomfort or uneasiness)
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Nasopharyngitis (inflammation of the nasopharynx)
- Night sweats (sweating in night)
male:
- Cough
- Death
- Blood pressure decreased
- Chest discomfort
- Chest pain
- Chills (felling of cold)
- Device dislocation
- Diarrhoea
- Dizziness
- Influenza
What are the common drug interactions of Klor-Con M20 and Opsumit, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Brain natriuretic peptide increased
- Chest pain
- Drug abuse
- Dyspnoea (difficult or laboured respiration)
- Haemorrhage (bleeding)
- Hospitalisation
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Right ventricular dysfunction
- Right ventricular failure (right half of the heart fails to work)
40-49:
- Cardiomegaly (increased size of heart than normal)
- Death
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Ill-defined disorder
- Laryngitis (inflammation of the larynx)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
- Thrombosis (formation of a blood clot inside a blood vessel)
50-59:
- Balance disorder
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diarrhoea
- Dizziness
- Fatigue (feeling of tiredness)
- Cardiomegaly (increased size of heart than normal)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
60+:
- Device failure
- Fatigue (feeling of tiredness)
- Peripheral swelling
- Arthralgia (joint pain)
- Arthropathy
- Blood iron decreased
- Chest discomfort
- Chills (felling of cold)
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 29 people, 69.05%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 11 people, 26.19%
* Approximation only. Some reports may have incomplete information.
Do you take Klor-con m20 and Opsumit?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Klor-con m20 (2,411 reports)
- Opsumit (67,926 reports)
Browse all drug interactions of Klor-con m20 and Opsumit:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Klor-con m20:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Opsumit:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Klor-con m20 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Opsumit and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on potassium chloride and macitentan (the active ingredients of Klor-con m20 and Opsumit, respectively), and Klor-con m20 and Opsumit (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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