Kyprolis and Cozaar drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Kyprolis (carfilzomib) and Cozaar (losartan potassium). Common drug interactions include pain among females and alopecia among males.
The phase IV clinical study analyzes what interactions people have when they take Kyprolis and Cozaar. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Kyprolis?
Kyprolis has active ingredients of carfilzomib. It is often used in multiple myeloma. eHealthMe is studying from 15,080 Kyprolis users. Check the latest studies of Kyprolis.
What is Cozaar?
Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.
19 people who take Kyprolis and Cozaar together, and have interactions are studied.

What are the common drug interactions of Kyprolis and Cozaar, by gender? *:
female:
- Pain
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Anuria (failure of the kidneys to produce urine)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Generalised oedema (swelling all over the body)
- Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
- Renal impairment (severely reduced kidney function)
- Viral upper respiratory tract infection
- Balance disorder
- Dizziness
male:
- Alopecia (absence of hair from areas of the body)
- Dehydration (dryness resulting from the removal of water)
- Febrile neutropenia (fever with reduced white blood cells)
- Feeling jittery
- Heat illness
- Hypotension (abnormally low blood pressure)
- Influenza
- Influenza like illness
- Insomnia (sleeplessness)
- Malaise (a feeling of general discomfort or uneasiness)
What are the common drug interactions of Kyprolis and Cozaar, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Anuria (failure of the kidneys to produce urine)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Generalised oedema (swelling all over the body)
- Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
- Renal impairment (severely reduced kidney function)
60+:
- Alopecia (absence of hair from areas of the body)
- Weight decreased
- Fall
- Febrile neutropenia (fever with reduced white blood cells)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Hypotension (abnormally low blood pressure)
- Malaise (a feeling of general discomfort or uneasiness)
- Muscular weakness (muscle weakness)
- Pain
- Palpitations (feelings or sensations that your heart is pounding or racing)
What are the existing conditions these people have? *
- Pain: 2 people, 10.53%
- Monoclonal Gammopathy: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Kyprolis and Cozaar?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Kyprolis and Cozaar:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Kyprolis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cozaar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kyprolis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cozaar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on carfilzomib and losartan potassium (the active ingredients of Kyprolis and Cozaar, respectively), and Kyprolis and Cozaar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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