L-methylfolate and Bethkis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take L-methylfolate (folic acid) and Bethkis (tobramycin). Common drug interactions include hospitalisation among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take L-methylfolate and Bethkis. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is L-methylfolate?

L-methylfolate has active ingredients of folic acid. It is often used in depression. eHealthMe is studying from 619 L-methylfolate users. Check the latest studies of L-methylfolate.

What is Bethkis?

Bethkis has active ingredients of tobramycin. eHealthMe is studying from 2,409 Bethkis users. Check the latest studies of Bethkis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

12 people who take L-methylfolate and Bethkis together, and have interactions are studied.

L-methylfolate and Bethkis drug interactions.

What are the common drug interactions of L-Methylfolate and Bethkis, by gender? *:

female:

Hospitalisation
Infection

male:

Pyrexia (fever)
Acidosis (build-up of carbon dioxide in the blood)
Constipation
Cough
Cystic fibrosis (disease of the secretary glands)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the common drug interactions of L-Methylfolate and Bethkis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hospitalisation

20-29:

n/a

30-39:

Pyrexia (fever)
Acidosis (build-up of carbon dioxide in the blood)
Constipation
Cough
Cystic fibrosis (disease of the secretary glands)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 12 people, 100.00%
Pain: 10 people, 83.33%
Nasal Discomfort: 10 people, 83.33%
Wheezing (a high-pitched whistling sound made while you breath): 9 people, 75.00%
Sedation: 9 people, 75.00%
Asthma: 9 people, 75.00%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 9 people, 75.00%
Blood Glucose Decreased: 9 people, 75.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 9 people, 75.00%
Cough: 9 people, 75.00%

* Approximation only. Some reports may have incomplete information.

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