L-methylfolate and Fish oil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take L-methylfolate (folic acid) and Fish oil (fish oil). Common drug interactions include pulmonary thrombosis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take L-methylfolate and Fish oil. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is L-methylfolate?

L-methylfolate has active ingredients of folic acid. It is often used in depression. eHealthMe is studying from 619 L-methylfolate users. Check the latest studies of L-methylfolate.

What is Fish oil?

Fish oil has active ingredients of fish oil. It is often used in high blood cholesterol. eHealthMe is studying from 112,933 Fish oil users. Check the latest studies of Fish oil.

On Jul, 28, 2026

74 people who take L-methylfolate and Fish oil together, and have interactions are studied.

L-methylfolate and Fish oil drug interactions.

What are the common drug interactions of L-Methylfolate and Fish Oil, by gender? *:

female:

Pulmonary thrombosis (scarring in the lungs)
Respiratory syncytial virus infection (viral disease of respiratory system)
Therapeutic response decreased (less preventive response)
Therapeutic response unexpected
Vomiting
Malaise (a feeling of general discomfort or uneasiness)
Stomatitis (inflammation of mucous membrane of mouth)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Alopecia (absence of hair from areas of the body)
Anxiety

male:

Diarrhoea
Oxygen saturation decreased
Gastritis (inflammation of stomach)
Nausea (feeling of having an urge to vomit)
Presyncope
Urinary tract infection
Vision blurred
Vitamin b6 decreased
Vitamin d decreased
Weight decreased

What are the common drug interactions of L-Methylfolate and Fish Oil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Herpes zoster
Muscle spasms (muscle contraction)
Post herpetic neuralgia (neuralgia caused by the varicella zoster virus)
Uterine pain
Granulocytopenia (lack of granulocyte)
Haemorrhage (bleeding)

30-39:

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)

40-49:

Breast mass
Injection site pain
Middle ear effusion (fluid in middle ear)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Respiratory tract infection viral
Urinary tract infection
Weight decreased
Anal fissure
Erythema (redness of the skin)
Influenza

50-59:

Tremor (trembling or shaking movements in one or more parts of your body)
Gait disturbance
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Pain
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Balance disorder
Chondropathy (disease of the cartilage)
Drug ineffective
Fall

60+:

Restless legs syndrome (a powerful urge to move your legs)
Anaemia (lack of blood)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Haemorrhage (bleeding)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Pruritus (severe itching of the skin)
Skin exfoliation (removal of the oldest dead skin cells)
Skin fissures (a crack in the skin)
Urinary tract infection
Stomatitis (inflammation of mucous membrane of mouth)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 22 people, 29.73%
Immunodeficiency Common Variable: 12 people, 16.22%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 14.86%
Pain: 9 people, 12.16%
Sleep Disorder: 6 people, 8.11%
Constipation: 6 people, 8.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.11%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 8.11%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 6.76%
Impaired Gastric Emptying: 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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