Labetalol hydrochloride and Spironolactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Labetalol hydrochloride (labetalol hydrochloride) and Spironolactone (spironolactone). Common drug interactions include palpitations among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Labetalol hydrochloride and Spironolactone. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Labetalol hydrochloride?

Labetalol hydrochloride has active ingredients of labetalol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,413 Labetalol hydrochloride users. Check the latest studies of Labetalol hydrochloride.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

On Jul, 06, 2026

42 people who take Labetalol hydrochloride and Spironolactone together, and have interactions are studied.

Labetalol hydrochloride and Spironolactone drug interactions.

What are the common drug interactions of Labetalol Hydrochloride and Spironolactone, by gender? *:

female:

Palpitations (feelings or sensations that your heart is pounding or racing)
Renal injury (kidney injury)
Upper respiratory tract infection
Cerebral haemorrhage (bleeding within the brain)
Confusional state
Cough
Death
Headache (pain in head)
Memory impairment
Neuropathy peripheral (surface nerve damage)

male:

Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Abdominal rigidity
Arthralgia (joint pain)
Blood pressure decreased
Contusion (a type of hematoma of tissue in which capillaries)
Dyspnoea (difficult or laboured respiration)
Fall
General physical health deterioration (weak health status)
Head injury

What are the common drug interactions of Labetalol Hydrochloride and Spironolactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cerebral haemorrhage (bleeding within the brain)
Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)

10-19:

n/a

20-29:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

30-39:

Neuropathy peripheral (surface nerve damage)

40-49:

Chest pain
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Dizziness
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Fall
Fatigue (feeling of tiredness)
Head injury

50-59:

n/a

60+:

Asthenia (weakness)
Cough
Pneumonia
Renal failure (kidney dysfunction)
Sinusitis (inflammation of sinus)
Abdominal hernia
Abdominal pain upper
Abdominal tenderness
Abnormal sleep-related event
Anaemia (lack of blood)

What are the existing conditions these people have? *

Stress And Anxiety: 5 people, 11.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.90%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 9.52%
Chest Pain: 4 people, 9.52%
Nausea (feeling of having an urge to vomit): 4 people, 9.52%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 9.52%
High Blood Cholesterol: 3 people, 7.14%
Cardiac Disorder: 3 people, 7.14%
Drowsiness: 3 people, 7.14%
Gastric Ulcer (stomach ulcer): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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