Lactulose and Cosentyx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lactulose (lactulose) and Cosentyx (secukinumab). Common drug interactions include headache among females and erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Lactulose and Cosentyx. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.



On Jul, 16, 2026

76 people who take Lactulose and Cosentyx together, and have interactions are studied.

Lactulose and Cosentyx drug interactions.

What are the common drug interactions of Lactulose and Cosentyx, by gender? *:

female:

  1. Headache (pain in head)
  2. Memory impairment
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Escherichia urinary tract infection (urinary tract infection by escherichia coli)
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Rhinorrhoea (watery mucus discharge from the nose)
  7. Catatonia (unresponsive to external stimuli)
  8. Fall
  9. Hepatomegaly (abnormal enlargement of the liver)
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

male:

  1. Erythema (redness of the skin)
  2. Pruritus (severe itching of the skin)
  3. Scratch
  4. Skin fragility (trauma-induced blisters and erosions of skin)
  5. Thermal burn (burn by heat)
  6. Pyrexia (fever)
  7. Pain of skin
  8. Sinusitis (inflammation of sinus)
  9. Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer)
  10. Emotional distress

What are the common drug interactions of Lactulose and Cosentyx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Delivery
  2. Gestational diabetes (diabetes in pregnancy)
  3. Live birth
  4. Maternal exposure during pregnancy (use of substance during pregnancy)
  5. Normal newborn
  6. Psoriasis (immune-mediated disease that affects the skin)

30-39:

  1. Pancreatitis acute (sudden inflammation of pancreas)
  2. Vomiting
  3. Abdominal pain
  4. Abdominal pain upper
  5. Agitation (state of anxiety or nervous excitement)
  6. Alcoholic pancreatitis
  7. Dyspnoea (difficult or laboured respiration)
  8. Hyperventilation
  9. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  10. Nausea (feeling of having an urge to vomit)

40-49:

  1. Circulatory collapse
  2. Delirium (wild excitement)
  3. Dyspnoea (difficult or laboured respiration)
  4. Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)
  5. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  6. Ketoacidosis (high concentrations of ketone bodies in blood)
  7. Megacolon (a very dilated colon)
  8. Septic shock (shock due to blood infection)
  9. Abdominal distension
  10. Abdominal pain

50-59:

  1. Infection
  2. Pain of skin
  3. Pruritus generalised (generalized itching)
  4. Pyrexia (fever)
  5. Acute abdomen
  6. Circulatory collapse
  7. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  8. Depression
  9. Drug ineffective
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Asthenia (weakness)
  2. Pruritus (severe itching of the skin)
  3. Pain
  4. Pain of skin
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Pyrexia (fever)
  7. Scratch
  8. Sinusitis (inflammation of sinus)
  9. Skin fragility (trauma-induced blisters and erosions of skin)
  10. Skin plaque (red, scaly patches to appear on the skin)

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 61 people, 80.26%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 20 people, 26.32%
  3. High Blood Pressure: 14 people, 18.42%
  4. Pain: 11 people, 14.47%
  5. Itching: 8 people, 10.53%
  6. Folate Deficiency (lack of folic acid): 7 people, 9.21%
  7. Indigestion: 7 people, 9.21%
  8. Anaemia (lack of blood): 7 people, 9.21%
  9. Joint Pain: 6 people, 7.89%
  10. Hypersensitivity: 6 people, 7.89%

* Approximation only. Some reports may have incomplete information.

Do you take Lactulose and Cosentyx?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lactulose and Cosentyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lactulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cosentyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lactulose and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cosentyx and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lactulose and secukinumab (the active ingredients of Lactulose and Cosentyx, respectively), and Lactulose and Cosentyx (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: