Lactulose and Darzalex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lactulose (lactulose) and Darzalex (daratumumab). Common drug interactions include hyperammonaemia among females and blood pressure decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Lactulose and Darzalex. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

What is Darzalex?

Darzalex has active ingredients of daratumumab. eHealthMe is studying from 20,206 Darzalex users. Check the latest studies of Darzalex.

On Jul, 08, 2026

36 people who take Lactulose and Darzalex together, and have interactions are studied.

Lactulose and Darzalex drug interactions.

What are the common drug interactions of Lactulose and Darzalex, by gender? *:

female:

Hyperammonaemia
Leukoencephalopathy (disease of the white matter in the brain)
Plasma cell myeloma (cancer that begins in plasma cells)
Neutropenia (an abnormally low number of neutrophils)
Abdominal pain
Diarrhoea
Escherichia sepsis (bacterial infection by escherichia coli)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)

male:

Blood pressure decreased
Cardiac failure acute
Blood pressure increased
Chills (felling of cold)
Confusional state
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Dysstasia (difficulty in standing)
Eye irritation
Gastric infection (infection of stomach)

What are the common drug interactions of Lactulose and Darzalex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood pressure increased
Infusion related reaction
Oxygen saturation decreased

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Neutropenia (an abnormally low number of neutrophils)
Pulmonary embolism (blockage of the main artery of the lung)

60+:

Hyperammonaemia
Leukoencephalopathy (disease of the white matter in the brain)
Escherichia sepsis (bacterial infection by escherichia coli)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pyrexia (fever)
Rhinovirus infection
Vomiting

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 30 people, 83.33%
Nausea (feeling of having an urge to vomit): 6 people, 16.67%
Pain: 4 people, 11.11%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 4 people, 11.11%
Liver Disorder (liver diseases): 4 people, 11.11%
Hypersensitivity: 4 people, 11.11%
Joint Pain: 3 people, 8.33%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 8.33%
High Blood Pressure: 3 people, 8.33%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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