Lactulose and Peginterferon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lactulose (lactulose) and Peginterferon (peginterferon alfa-2a; ribavirin). Common drug interactions include decreased appetite among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Lactulose and Peginterferon. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

What is Peginterferon?

Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,778 Peginterferon users. Check the latest studies of Peginterferon.



On Jul, 31, 2026

47 people who take Lactulose and Peginterferon together, and have interactions are studied.

Lactulose and Peginterferon drug interactions.

What are the common drug interactions of Lactulose and Peginterferon, by gender? *:

female:

  1. Decreased appetite
  2. Device related infection
  3. Diarrhoea
  4. Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
  5. Dry mouth
  6. Dyspnoea (difficult or laboured respiration)
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  8. Epistaxis (bleed from the nose)
  9. Erythema (redness of the skin)
  10. Fatigue (feeling of tiredness)

male:

  1. Anaemia (lack of blood)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Diarrhoea
  4. Dyspnoea (difficult or laboured respiration)
  5. Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
  6. Oedema peripheral (superficial swelling)
  7. Oral candidiasis (fungal infection of mouth)
  8. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  9. Acute hepatic failure
  10. Ascites (accumulation of fluid in the abdominal cavity)

What are the common drug interactions of Lactulose and Peginterferon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Feeding tube complication
  2. Food intolerance (inability to have food)
  3. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  4. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  5. Hypophagia (reduced food intake)
  6. Injection site erythema (redness at injection site)
  7. Ischaemic gastritis (inflammation of the lining of the stomach due to inadequate supply of blood)
  8. Multi-organ failure (multisystem organ failure)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Oral pain

50-59:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Blood bilirubin increased
  4. Chronic hepatic failure (long lasting liver failure)
  5. Diarrhoea
  6. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  7. Thrombocytopenia (decrease of platelets in blood)
  8. Loss of consciousness
  9. Bone marrow failure
  10. Dehydration (dryness resulting from the removal of water)

60+:

  1. Blood bilirubin increased
  2. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  3. Anaemia (lack of blood)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Asthma
  7. Head injury
  8. Headache (pain in head)
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Influenza

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 12.77%
  2. Diabetes: 6 people, 12.77%
  3. Pain: 4 people, 8.51%
  4. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 4 people, 8.51%
  5. Insomnia (sleeplessness): 3 people, 6.38%
  6. Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

Do you take Lactulose and Peginterferon?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lactulose and Peginterferon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lactulose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Peginterferon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lactulose and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peginterferon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lactulose and peginterferon alfa-2a; ribavirin (the active ingredients of Lactulose and Peginterferon, respectively), and Lactulose and Peginterferon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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