Lamisil and Otezla drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Otezla (apremilast). Common drug interactions include fall among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Otezla. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Otezla?

Otezla has active ingredients of apremilast. It is often used in psoriatic arthritis. eHealthMe is studying from 146,254 Otezla users. Check the latest studies of Otezla.

On Jul, 17, 2026

62 people who take Lamisil and Otezla together, and have interactions are studied.

What are the common drug interactions of Lamisil and Otezla, by gender? *:

female:

Fall
Anxiety
Back pain
Contusion (a type of hematoma of tissue in which capillaries)
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Headache (pain in head)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Infection
Pain in extremity

male:

Diarrhoea
Chlamydial infection (a common sexually transmitted infection (sti) in humans caused by the bacterium chlamydia trachomatis)
Application site discolouration
Blood alkaline phosphatase increased
Erythema (redness of the skin)
Nephritis (inflammation of the nephrons in the kidneys)
Neuralgia (pain in one or more nerves)
Skin exfoliation (removal of the oldest dead skin cells)
Ureteric obstruction
Cardiac failure

What are the common drug interactions of Lamisil and Otezla, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Application site discolouration
Erythema (redness of the skin)
Skin exfoliation (removal of the oldest dead skin cells)

40-49:

Headache (pain in head)
Nephritis (inflammation of the nephrons in the kidneys)
Neuralgia (pain in one or more nerves)
Psoriasis (immune-mediated disease that affects the skin)
Rectal cancer recurrent (reoccurrence of rectum cancer)
Surgery
Ureteric obstruction

50-59:

Psoriasis (immune-mediated disease that affects the skin)
Lower respiratory tract infection
Injection site bruising
Abdominal distension
Abdominal pain upper
Diarrhoea
Hypersensitivity

60+:

Anxiety
Back pain
Peripheral swelling
Poor quality sleep
Renal disorder (kidney disease)
Sensory disturbance (sense disturbance)
Skin atrophy (wasting of skin)
Skin discolouration (change of skin colour)
Syncope (loss of consciousness with an inability to maintain postural tone)
Weight decreased

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 52 people, 83.87%
High Blood Pressure: 10 people, 16.13%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 12.90%
Athlete's Foot (a fungal infection affecting the skin between the toes): 6 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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