Lamisil and Paracetamol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Paracetamol (acetaminophen). Common drug interactions include myalgia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Paracetamol. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 19, 2026

44 people who take Lamisil and Paracetamol together, and have interactions are studied.

Lamisil and Paracetamol drug interactions.

What are the common drug interactions of Lamisil and Paracetamol, by gender? *:

female:

  1. Myalgia (muscle pain)
  2. Nausea (feeling of having an urge to vomit)
  3. Nightmare (unpleasant dream)
  4. Ocular hyperaemia (an abnormally large amount of blood in eye)
  5. Oedema (fluid collection in tissue)
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Pelvic pain
  8. Personality disorder
  9. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  10. Platelet count decreased

male:

  1. Pneumonia
  2. Gastrointestinal angiodysplasia (a small vascular malformation of the gut)
  3. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Cellulitis (infection under the skin)
  6. Dehydration (dryness resulting from the removal of water)
  7. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  8. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  9. Hydronephrosis (water inside the kidney)
  10. Hypokalaemia (low potassium)

What are the common drug interactions of Lamisil and Paracetamol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Vaginal infection
  2. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  3. Rash erythematous (redness of the skin)
  4. Swelling

40-49:

  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Anaemia (lack of blood)
  4. Cellulitis (infection under the skin)
  5. Dehydration (dryness resulting from the removal of water)
  6. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  7. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  8. Hydronephrosis (water inside the kidney)
  9. Hypokalaemia (low potassium)
  10. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

50-59:

  1. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  2. Atrophic vulvovaginitis (inflammation of the vulva)
  3. Back pain
  4. Cardiac disorder
  5. Community acquired infection (infection from community rather than hospital)
  6. Cystitis (inflammation of the wall of the bladder)
  7. Haemorrhage (bleeding)
  8. Haemorrhage subcutaneous (bleeding from skin)
  9. Hyperuricaemia (level of uric acid in the blood that is abnormally high)
  10. Oedema (fluid collection in tissue)

60+:

  1. Pneumonia
  2. Gastrointestinal angiodysplasia (a small vascular malformation of the gut)
  3. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
  4. Anxiety
  5. Back pain
  6. Blood pressure decreased
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Dyspnoea (difficult or laboured respiration)
  9. Dysuria (painful or difficult urination)
  10. Fall

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 21 people, 47.73%
  2. Constipation: 4 people, 9.09%
  3. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 6.82%
  4. Depression: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Lamisil and Paracetamol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamisil and Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamisil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamisil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paracetamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on terbinafine hydrochloride and acetaminophen (the active ingredients of Lamisil and Paracetamol, respectively), and Lamisil and Paracetamol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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