Lamisil and Samsca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Samsca (tolvaptan). Common drug interactions include adrenal insufficiency among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Samsca. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Samsca?

Samsca has active ingredients of tolvaptan. eHealthMe is studying from 8,139 Samsca users. Check the latest studies of Samsca.

On Jul, 10, 2026

11 people who take Lamisil and Samsca together, and have interactions are studied.

What are the common drug interactions of Lamisil and Samsca, by gender? *:

female:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Herpes zoster
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Pneumonia
Tinea infection (fungal skin infection)
Thyroiditis subacute (inflammation of thyroid gland less severe and less durational)
Fracture
Right ventricular failure (right half of the heart fails to work)
Upper respiratory tract inflammation
Blood urea increased

male:

Anaemia (lack of blood)
Cellulitis (infection under the skin)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Oesophageal candidiasis (fungal infection of oesophagus)
Panniculitis (inflammation of the subcutaneous fat)
Tinea pedis (a contagious skin infection caused by the ringworm fungus)
Abscess limb (limb infection)
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
C-reactive protein increased
Constipation

What are the common drug interactions of Lamisil and Samsca, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abscess limb (limb infection)
Anaemia (lack of blood)
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
C-reactive protein increased
Cellulitis (infection under the skin)
Constipation
Erectile dysfunction
Femur fracture
Folliculitis (infection of hair root)
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)

50-59:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Herpes zoster
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Pneumonia
Tinea infection (fungal skin infection)
Thyroiditis subacute (inflammation of thyroid gland less severe and less durational)
Fracture
Right ventricular failure (right half of the heart fails to work)
Upper respiratory tract inflammation
Anaemia (lack of blood)

60+:

Acute hepatic failure
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Oedema peripheral (superficial swelling)
Rash
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin lesion
Transaminases increased
Urinary retention (the inability to completely or partially empty the bladder)

What are the existing conditions these people have? *

Interstitial Lung Disease: 6 people, 54.55%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 54.55%
Urination - Painful: 3 people, 27.27%
Constipation: 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Oedema Peripheral (superficial swelling): 3 people, 27.27%
Mycobacterium Avium Complex Infection: 3 people, 27.27%
Hiv Infection: 3 people, 27.27%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 27.27%
Gastritis (inflammation of stomach): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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