Lamisil and Serzone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Serzone (nefazodone hydrochloride). Common drug interactions include premenstrual syndrome among females and suicidal ideation among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Serzone. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Serzone?

Serzone has active ingredients of nefazodone hydrochloride. It is often used in depression. eHealthMe is studying from 7,695 Serzone users. Check the latest studies of Serzone.



On Jul, 07, 2026

33 people who take Lamisil and Serzone together, and have interactions are studied.

Lamisil and Serzone drug interactions.

What are the common drug interactions of Lamisil and Serzone, by gender? *:

female:

  1. Premenstrual syndrome
  2. Presbyopia (a condition in which the lens of the eye loses its ability to focus, making it difficult to see objects up close)
  3. Schizoaffective disorder (a mental disorder characterized by disordered thought)
  4. Sleep disorder
  5. Tobacco abuse
  6. Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
  7. Vitamin b12 deficiency
  8. Vulvovaginal candidiasis (vulvovaginal infection by fungi)
  9. Weight increased
  10. Insomnia (sleeplessness)

male:

  1. Suicidal ideation
  2. Emotional distress
  3. Ligament sprain (ligament stretched)
  4. Memory impairment
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Nausea (feeling of having an urge to vomit)
  7. Overdose
  8. Pain in extremity
  9. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  10. Spinal cord disorder (disease of spinal cord)

What are the common drug interactions of Lamisil and Serzone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  2. Diarrhoea
  3. Drug dependence
  4. Dyspepsia (indigestion)
  5. Dyspnoea (difficult or laboured respiration)
  6. Gingival bleeding (bleeding gums)
  7. Hypercholesterolaemia (high levels of cholesterol in the blood)
  8. Hypertriglyceridaemia (excess of triglycerides in the blood)
  9. Incontinence (lack of moderation or self-control)
  10. Menstruation irregular

40-49:

  1. Chest pain
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Headache (pain in head)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Abdominal distension
  6. Abdominal pain
  7. Affect lability (emotional incontinence)
  8. Bradycardia (abnormally slow heart action)
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Choking (mechanical obstruction of the flow of air from the environment into the lungs)

50-59:

  1. Overdose
  2. Pain in extremity
  3. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  4. Spinal cord disorder (disease of spinal cord)
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Blindness unilateral
  7. Cognitive deterioration (memory impairment)
  8. Difficulty in walking
  9. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  10. Hypersomnia (excessive daytime sleepiness (eds))

60+:

  1. Hypersensitivity
  2. Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 11 people, 33.33%
  2. Bipolar Disorder (mood disorder): 9 people, 27.27%
  3. High Blood Pressure: 8 people, 24.24%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 15.15%
  5. Sleep Disorder: 4 people, 12.12%
  6. Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 12.12%
  7. Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 12.12%
  8. Joint Pain: 4 people, 12.12%
  9. High Blood Cholesterol: 4 people, 12.12%
  10. Headache (pain in head): 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

Do you take Lamisil and Serzone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamisil and Serzone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamisil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Serzone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamisil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Serzone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on terbinafine hydrochloride and nefazodone hydrochloride (the active ingredients of Lamisil and Serzone, respectively), and Lamisil and Serzone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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