Lamotrigine and Avelox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Avelox (moxifloxacin hydrochloride). Common drug interactions include joint injury among females and neuropathy peripheral among males.
The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Avelox. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Lamotrigine?
Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.
What is Avelox?
Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.
36 people who take Lamotrigine and Avelox together, and have interactions are studied.

What are the common drug interactions of Lamotrigine and Avelox, by gender? *:
female:
- Joint injury
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Nausea (feeling of having an urge to vomit)
- Pain
- Plantar fascial fibromatosis (non-malignant thickening of the feet's deep connective tissue)
- Relapsing-remitting multiple sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged)
- Anxiety
- Asthenia (weakness)
- Burning sensation
- Dyspnoea (difficult or laboured respiration)
male:
- Neuropathy peripheral (surface nerve damage)
- Muscular weakness (muscle weakness)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Diplopia (double vision)
- Drug dependence
- Dysarthria (speech disorder)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dysstasia (difficulty in standing)
- Gingival hypertrophy (overgrowth of gums)
- Impaired driving ability
What are the common drug interactions of Lamotrigine and Avelox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- General physical health deterioration (weak health status)
- Injury
- Pain
- Pulmonary embolism (blockage of the main artery of the lung)
30-39:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Brain neoplasm (tumour of brain)
- Chronic kidney disease
- Diabetic coma
- Drug ineffective
- Erythema (redness of the skin)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypoaesthesia (reduced sense of touch or sensation)
- Nausea (feeling of having an urge to vomit)
40-49:
- Renal failure (kidney dysfunction)
- Depression
- Arthralgia (joint pain)
- Asthenia (weakness)
- Burning sensation
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Chest pain
- Fall
- Head injury
- Hypoaesthesia (reduced sense of touch or sensation)
50-59:
- Osteoporosis (bones weak and more likely to break)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Ataxia (loss of full control of bodily movements)
- Atelectasis (partial or complete collapse of the lung)
- Balance disorder
- Bone metabolism disorder
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Diplopia (double vision)
60+:
- Chronic kidney disease
- Agitation (state of anxiety or nervous excitement)
- Pain
- Quality of life decreased
- Renal failure (kidney dysfunction)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Carcinoid syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction)
- Cheilitis (infection of lips)
- Chest pain
What are the existing conditions these people have? *
- Pain: 17 people, 47.22%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 41.67%
- Insomnia (sleeplessness): 8 people, 22.22%
- Stress And Anxiety: 7 people, 19.44%
- Infection: 7 people, 19.44%
- Nausea (feeling of having an urge to vomit): 7 people, 19.44%
- High Blood Pressure: 6 people, 16.67%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 16.67%
- Depression: 5 people, 13.89%
- Constipation: 5 people, 13.89%
* Approximation only. Some reports may have incomplete information.
Do you take Lamotrigine and Avelox?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lamotrigine (76,638 reports)
- Avelox (28,651 reports)
Browse all drug interactions of Lamotrigine and Avelox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lamotrigine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Avelox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lamotrigine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avelox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on lamotrigine and moxifloxacin hydrochloride (the active ingredients of Lamotrigine and Avelox, respectively), and Lamotrigine and Avelox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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