Lamotrigine and Exjade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Exjade (deferasirox). Common drug interactions include nausea among females and clostridium difficile colitis among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Exjade. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Exjade?

Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.

On Jul, 17, 2026

11 people who take Lamotrigine and Exjade together, and have interactions are studied.

Lamotrigine and Exjade drug interactions.

What are the common drug interactions of Lamotrigine and Exjade, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Eye disorder
Frequent bowel movements
Hypoaesthesia (reduced sense of touch or sensation)
Muscle spasms (muscle contraction)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Gait disturbance
Hemiparesis (weakness on one side of the body)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Moyamoya disease (a disease in which certain arteries in the brain are constricted. blood flow is blocked by the constriction)
Pneumonia
Thrombosis (formation of a blood clot inside a blood vessel)
Varicella
Arthralgia (joint pain)

What are the common drug interactions of Lamotrigine and Exjade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Asthenia (weakness)
Blood glucose decreased
Blood pressure decreased
Colitis (inflammation of colon)
Coronary artery stenosis (narrowing of coronary artery)
Decreased appetite
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Pulmonary oedema (fluid accumulation in the lungs)
Staphylococcus test positive
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

30-39:

Abdominal pain upper
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Eye disorder
Frequent bowel movements
Hypoaesthesia (reduced sense of touch or sensation)
Muscle spasms (muscle contraction)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Serum ferritin increased

40-49:

Allergic granulomatous angiitis (allergic inflammation of a blood vessel or lymph duct)
Chest pain
Depression
Dyspepsia (indigestion)
Headache (pain in head)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)

50-59:

n/a

60+:

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Headache (pain in head)
Insomnia (sleeplessness)
Night sweats (sweating in night)
Migraine (headache)
Neoplasm malignant (cancer tumour)
Pain
Haemoglobin decreased
Lethargy (tiredness)

What are the existing conditions these people have? *

Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 5 people, 45.45%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 18.18%
Haemochromatosis (body to absorb more iron than usual from food): 2 people, 18.18%
Pain: 1 person, 9.09%
Migraine (headache): 1 person, 9.09%
Hypersensitivity: 1 person, 9.09%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%
Asthma: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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