1. Home
  2. Analysis
  3. Lamotrigine
  4. Feverfew

Lamotrigine and Feverfew drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Feverfew (feverfew). Common drug interactions include drug ineffective among females and cataplexy among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Feverfew. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Feverfew?

Feverfew has active ingredients of feverfew. It is often used in migraine. eHealthMe is studying from 217 Feverfew users. Check the latest studies of Feverfew.

On Jul, 06, 2026

16 people who take Lamotrigine and Feverfew together, and have interactions are studied.

Lamotrigine and Feverfew drug interactions.

What are the common drug interactions of Lamotrigine and Feverfew, by gender? *:

female:

  1. Drug ineffective
  2. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

male:

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  2. Stress
  3. Confusional state
  4. Laceration (tearing of soft body tissue)
  5. Loss of consciousness
  6. Sleep terror (felling of terror in sleep)
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Asthma
  9. Blood pressure increased
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Lamotrigine and Feverfew, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Drug ineffective
  2. Fatigue (feeling of tiredness)
  3. Pain

40-49:

n/a

50-59:

n/a

60+:

  1. Stress
  2. Anxiety
  3. Pain
  4. Sleep terror (felling of terror in sleep)
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Asthma
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Confusional state
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Fear

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 68.75%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 56.25%
  3. Osteomyelitis (infection of bone): 3 people, 18.75%
  4. Cellulitis (infection under the skin): 3 people, 18.75%
  5. Apnea (temporary absence or cessation of breathing): 3 people, 18.75%
  6. Drowsiness: 2 people, 12.50%
  7. Cuts And Puncture Wounds: 2 people, 12.50%
  8. Sleep Apnea Syndrome: 1 person, 6.25%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  10. Pain: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and Feverfew?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamotrigine and Feverfew:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Feverfew:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamotrigine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Feverfew and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine and feverfew (the active ingredients of Lamotrigine and Feverfew, respectively), and Lamotrigine and Feverfew (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.