Lamotrigine and Midol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Midol (ibuprofen). Common drug interactions include anxiety among females and plasma cell myeloma among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Midol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Midol?

Midol has active ingredients of ibuprofen. It is often used in painful menstrual periods. eHealthMe is studying from 2,635 Midol users. Check the latest studies of Midol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

13 people who take Lamotrigine and Midol together, and have interactions are studied.

Lamotrigine and Midol drug interactions.

What are the common drug interactions of Lamotrigine and Midol, by gender? *:

female:

Anxiety
Back pain
Bronchitis bacterial (inflammation of the mucous membrane in the bronchial tubes due to bacterial infection)
Confusional state
Fall
Hallucination (an experience involving the perception of something not present)
Head injury
Memory impairment
Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
Migraine (headache)

male:

Plasma cell myeloma (cancer that begins in plasma cells)
Bone pain
Dizziness
Tooth fracture

What are the common drug interactions of Lamotrigine and Midol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Hospitalisation
Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
Fatigue (feeling of tiredness)
Dysmenorrhoea (painful menstruation)
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)

30-39:

n/a

40-49:

Miliaria (a skin disease marked by small and itchy rashes)
Rash
Rash pruritic (redness with itching)

50-59:

n/a

60+:

Bone pain
Dizziness
Plasma cell myeloma (cancer that begins in plasma cells)
Tooth fracture

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 69.23%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 69.23%
Drowsiness: 3 people, 23.08%
Multiple Myeloma (cancer of the plasma cells): 3 people, 23.08%
Vitamin C Decreased: 2 people, 15.38%
Ill-Defined Disorder: 2 people, 15.38%
Birth Control: 2 people, 15.38%
Constipation: 2 people, 15.38%
Depression: 2 people, 15.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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