Lamotrigine and Viberzi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Viberzi (eluxadoline). Common drug interactions include hypoaesthesia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Viberzi. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,639 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Viberzi?

Viberzi has active ingredients of eluxadoline. eHealthMe is studying from 3,077 Viberzi users. Check the latest studies of Viberzi.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

18 people who take Lamotrigine and Viberzi together, and have interactions are studied.

Lamotrigine and Viberzi drug interactions.

What are the common drug interactions of Lamotrigine and Viberzi, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Gait disturbance
Haematoma (collection of blood outside the blood vessels)
Headache (pain in head)

male:

Anxiety
Decreased interest
Somnolence (a state of near-sleep, a strong desire for sleep)
Depression
Emotional distress
Fibromyalgia (a long-term condition which causes pain all over the body)
Impaired work ability
Ligament rupture (tear in ligament)
Mania (a state of abnormally elevated or irritable mood)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)

What are the common drug interactions of Lamotrigine and Viberzi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Decreased interest
Depression
Emotional distress
Fibromyalgia (a long-term condition which causes pain all over the body)
Impaired work ability
Ligament rupture (tear in ligament)
Mania (a state of abnormally elevated or irritable mood)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Pain

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hypoaesthesia (reduced sense of touch or sensation)
Malaise (a feeling of general discomfort or uneasiness)
Poor venous access
Sinusitis (inflammation of sinus)
Viral infection
Fungal infection

50-59:

Blood pressure increased
Bone pain
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fall
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Fluid retention (an abnormal accumulation of fluid in the blood)
Fungal infection

60+:

Chronic kidney disease
Gout (uric acid crystals building up in the body)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 11 people, 61.11%
Pain: 5 people, 27.78%
Stress And Anxiety: 5 people, 27.78%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 22.22%
Nausea (feeling of having an urge to vomit): 4 people, 22.22%
Muscle Spasms (muscle contraction): 4 people, 22.22%
Mood Swings (an extreme or rapid change in mood): 4 people, 22.22%
Migraine (headache): 4 people, 22.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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