Lantus and Orenitram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lantus (insulin glargine recombinant) and Orenitram (treprostinil). Common drug interactions include respiratory failure among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Lantus and Orenitram. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

What is Orenitram?

Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.

On Jul, 13, 2026

80 people who take Lantus and Orenitram together, and have interactions are studied.

What are the common drug interactions of Lantus and Orenitram, by gender? *:

female:

Respiratory failure (inadequate gas exchange by the respiratory system)
Chest pain
Decreased appetite
Erythema (redness of the skin)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Abdominal pain upper
Burning sensation
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Nausea (feeling of having an urge to vomit)
Blood potassium increased
Headache (pain in head)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Adverse event
Influenza like illness
Respiratory failure (inadequate gas exchange by the respiratory system)
Anaemia (lack of blood)
Aphasia (damage to the parts of the brain that control language)

What are the common drug interactions of Lantus and Orenitram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nausea (feeling of having an urge to vomit)
Burning sensation
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyspnoea exertional (breathlessness or shortness of breath)
Irritability
Migraine (headache)
Pain
Pain in jaw
Palpitations (feelings or sensations that your heart is pounding or racing)
Dyspnoea (difficult or laboured respiration)

50-59:

Dyspnoea (difficult or laboured respiration)
Hemiparesis (weakness on one side of the body)
Hypoaesthesia (reduced sense of touch or sensation)
Impaired gastric emptying
Insomnia (sleeplessness)
Limb discomfort (discomfort in leg)
Pain
Pain in jaw
Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
Staphylococcal infection (an infection with staphylococcus bacteria)

60+:

Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Dyspnoea (difficult or laboured respiration)
Pneumonia
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blood glucose decreased
Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Contusion (a type of hematoma of tissue in which capillaries)
Hot flush (sudden feelings of heat)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 64 people, 80.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 14 people, 17.50%
High Blood Pressure: 5 people, 6.25%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 5.00%
Depression: 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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