Lariam and Lexapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lariam (mefloquine hydrochloride) and Lexapro (escitalopram oxalate). Common drug interactions include mental impairment among females and abnormal dreams among males.

The phase IV clinical study analyzes what interactions people have when they take Lariam and Lexapro. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Lariam?

Lariam has active ingredients of mefloquine hydrochloride. It is often used in malaria. eHealthMe is studying from 3,145 Lariam users. Check the latest studies of Lariam.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

On Jul, 14, 2026

19 people who take Lariam and Lexapro together, and have interactions are studied.

What are the common drug interactions of Lariam and Lexapro, by gender? *:

female:

Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Self-injurious ideation
Abnormal behaviour
Nervousness
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Pain
Panic attack
Abasia (inability to walk)
Abdominal discomfort

male:

Abnormal dreams
Fatigue (feeling of tiredness)
Ill-defined disorder
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pyrexia (fever)
Sleep disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Brain injury
Chemical injury

What are the common drug interactions of Lariam and Lexapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Panic attack
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)

30-39:

n/a

40-49:

Abnormal dreams
Fatigue (feeling of tiredness)
Ill-defined disorder
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pyrexia (fever)
Sleep disorder
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hot flush (sudden feelings of heat)
Insomnia (sleeplessness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Panic attack

60+:

Homicidal ideation (thoughts about human killing another human)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Abnormal sleep-related event
Agitation (state of anxiety or nervous excitement)
Alcohol use
Anger
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy

What are the existing conditions these people have? *

Quit Smoking: 13 people, 68.42%
Stress And Anxiety: 12 people, 63.16%
Back Pain: 12 people, 63.16%
Pain: 6 people, 31.58%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 6 people, 31.58%
Abdominal Discomfort: 6 people, 31.58%
Gastric Disorder (disease of stomach): 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

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