Leflunomide and Pataday drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leflunomide (leflunomide) and Pataday (olopatadine hydrochloride). Common drug interactions include influenza among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Leflunomide and Pataday. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Pataday?

Pataday has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 8,288 Pataday users. Check the latest studies of Pataday.

On Jul, 19, 2026

32 people who take Leflunomide and Pataday together, and have interactions are studied.

Leflunomide and Pataday drug interactions.

What are the common drug interactions of Leflunomide and Pataday, by gender? *:

female:

Influenza
Urticaria (rash of round, red welts on the skin that itch intensely)
Sinusitis (inflammation of sinus)
Headache (pain in head)
Leukopenia (less number of white blood cells in blood)
Nausea (feeling of having an urge to vomit)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Infusion related reaction

male:

Diarrhoea
Asthenia (weakness)
Headache (pain in head)
Migraine (headache)
Urinary tract infection
Chills (felling of cold)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dry mouth
Erectile dysfunction
Libido decreased (loss of interest in sex)

What are the common drug interactions of Leflunomide and Pataday, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Influenza
Sinusitis (inflammation of sinus)
Urticaria (rash of round, red welts on the skin that itch intensely)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Infusion related reaction

30-39:

n/a

40-49:

Headache (pain in head)
Leukopenia (less number of white blood cells in blood)
Nausea (feeling of having an urge to vomit)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

50-59:

Asthenia (weakness)
Cough
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Influenza
Lung disorder (lung disease)
Pancreatitis (inflammation of pancreas)
Peripheral vascular disorder
Productive cough
Pulmonary embolism (blockage of the main artery of the lung)

60+:

Diarrhoea
Asthenia (weakness)
Migraine (headache)
Urinary tract infection
Chills (felling of cold)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug ineffective
Fall
Head injury
Influenza

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 5 people, 15.62%
Pain: 4 people, 12.50%
Itching: 4 people, 12.50%
Migraine (headache): 3 people, 9.38%
Interstitial Lung Disease: 3 people, 9.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.25%
Asthma: 2 people, 6.25%
Cardiac Disorder: 2 people, 6.25%
Cough: 2 people, 6.25%
Diabetes: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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