Leflunomide and Prilosec otc drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leflunomide (leflunomide) and Prilosec otc (omeprazole magnesium). Common drug interactions include chronic kidney disease among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Leflunomide and Prilosec otc. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Prilosec otc?

Prilosec otc has active ingredients of omeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 38,394 Prilosec otc users. Check the latest studies of Prilosec otc.

On Jul, 07, 2026

16 people who take Leflunomide and Prilosec otc together, and have interactions are studied.

Leflunomide and Prilosec otc drug interactions.

What are the common drug interactions of Leflunomide and Prilosec Otc, by gender? *:

female:

Chronic kidney disease
Renal injury (kidney injury)
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Anaemia of chronic disease
Arthralgia (joint pain)
Weight increased
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Osteopenia (a condition where bone mineral density is lower than normal)
Gastrointestinal necrosis (destruction of gastrointestinal organ)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Muscle spasms (muscle contraction)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal injury (kidney injury)
Retinal disorder (disease of retina)
Visual field defect
Visual impairment
Nephrogenic anaemia (anaemia due to kidney disease)

What are the common drug interactions of Leflunomide and Prilosec Otc, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anaemia of chronic disease
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Osteopenia (a condition where bone mineral density is lower than normal)
Renal failure (kidney dysfunction)
Blindness
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug ineffective
Gastric disorder (disease of stomach)
Hypoaesthesia (reduced sense of touch or sensation)
Muscle spasms (muscle contraction)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Arthralgia (joint pain)
Peripheral swelling
Weight increased

What are the existing conditions these people have? *

Pain: 6 people, 37.50%
Infection: 5 people, 31.25%
Blood Pressure Abnormal: 5 people, 31.25%
Inflammation: 4 people, 25.00%
High Blood Pressure: 3 people, 18.75%
High Blood Cholesterol: 3 people, 18.75%
Neuralgia (pain in one or more nerves): 3 people, 18.75%
Diabetes: 3 people, 18.75%
Depression: 3 people, 18.75%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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