Lemtrada and Nexium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lemtrada (alemtuzumab) and Nexium (esomeprazole magnesium). Common drug interactions include gait disturbance among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Lemtrada and Nexium. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Lemtrada?
Lemtrada has active ingredients of alemtuzumab. eHealthMe is studying from 8,317 Lemtrada users. Check the latest studies of Lemtrada.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.
13 people who take Lemtrada and Nexium together, and have interactions are studied.

What are the common drug interactions of Lemtrada and Nexium, by gender? *:
female:
- Gait disturbance
- Herpes zoster
- Urinary tract infection
- Balance disorder
- Chills (felling of cold)
- Headache (pain in head)
- Hemiparesis (weakness on one side of the body)
- Hypoaesthesia (reduced sense of touch or sensation)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Pain
male:
- Dyspnoea (difficult or laboured respiration)
- White blood cell count decreased
- Blood urine present
- Carbon dioxide decreased
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Chills (felling of cold)
- Coagulopathy (blood's ability to clot is impaired)
- Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
- Constipation
- Dysphagia (a condition in which swallowing is difficult or painful)
What are the common drug interactions of Lemtrada and Nexium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Haematuria (presence of blood in urine)
- Hypoaesthesia (reduced sense of touch or sensation)
- Nasopharyngitis (inflammation of the nasopharynx)
- Abdominal pain
- Acquired haemophilia (bleeding disorder disease)
- Blood glucose increased
- Blood potassium decreased
- Blood urine present
- Carbon dioxide decreased
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
30-39:
- Abortion (termination of pregnancy)
- Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
- Herpes zoster
- Nausea (feeling of having an urge to vomit)
- Oral herpes (viral infection of mouth)
- Rash
- Sinus bradycardia (an unusually slow heartbeat due to heart disease)
- Urinary tract infection
- White blood cells urine positive
40-49:
n/a
50-59:
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Fall
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Constipation
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Hot flush (sudden feelings of heat)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
60+:
- Balance disorder
- Chills (felling of cold)
- Stress
- Oral infection
- Gait disturbance
- Headache (pain in head)
- Hemiparesis (weakness on one side of the body)
- Herpes zoster
- Hypoaesthesia (reduced sense of touch or sensation)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
What are the existing conditions these people have? *
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 38.46%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 15.38%
- Headache (pain in head): 2 people, 15.38%
- Progressive Relapsing Multiple Sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord or both): 1 person, 7.69%
- Pain: 1 person, 7.69%
- Nausea (feeling of having an urge to vomit): 1 person, 7.69%
- Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
- Gastric Ulcer (stomach ulcer): 1 person, 7.69%
- Gait Disturbance: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Lemtrada and Nexium?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lemtrada and Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lemtrada:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lemtrada and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nexium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on alemtuzumab and esomeprazole magnesium (the active ingredients of Lemtrada and Nexium, respectively), and Lemtrada and Nexium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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