Lenalidomide and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lenalidomide (lenalidomide) and Clonidine (clonidine). Common drug interactions include fall among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Lenalidomide and Clonidine. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

91 people who take Lenalidomide and Clonidine together, and have interactions are studied.

Lenalidomide and Clonidine drug interactions.

What are the common drug interactions of Lenalidomide and Clonidine, by gender? *:

female:

  1. Fall
  2. Dyspnoea (difficult or laboured respiration)
  3. Pain
  4. Platelet count decreased
  5. Pyrexia (fever)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Asthenia (weakness)
  8. Back pain
  9. Dehydration (dryness resulting from the removal of water)
  10. Fatigue (feeling of tiredness)

male:

  1. Fall
  2. Asthma
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Asthenia (weakness)
  5. Diarrhoea
  6. Sinus bradycardia (an unusually slow heartbeat due to heart disease)
  7. Fatigue (feeling of tiredness)
  8. Swelling
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the common drug interactions of Lenalidomide and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Plasma cell myeloma (cancer that begins in plasma cells)
  2. Pneumonia

50-59:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Fall
  3. Headache (pain in head)
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  5. Pain
  6. Drug ineffective
  7. Renal impairment (severely reduced kidney function)
  8. Anaemia (lack of blood)
  9. Blood potassium decreased
  10. Blood pressure inadequately controlled

60+:

  1. Fall
  2. Asthenia (weakness)
  3. Back pain
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Dehydration (dryness resulting from the removal of water)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Acquired oesophageal web (structural abnormalities in the oesophagus)
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Anaemia (lack of blood)
  10. Arteriosclerosis (thickening and hardening of arteries)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 66 people, 72.53%
  2. Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 5.49%
  3. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 5 people, 5.49%

* Approximation only. Some reports may have incomplete information.

Do you take Lenalidomide and Clonidine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lenalidomide and Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lenalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lenalidomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lenalidomide and clonidine (the active ingredients of Lenalidomide and Clonidine, respectively), and Lenalidomide and Clonidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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