Lenalidomide and Jardiance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lenalidomide (lenalidomide) and Jardiance (empagliflozin). Common drug interactions include coma among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Lenalidomide and Jardiance. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,457 Jardiance users. Check the latest studies of Jardiance.



On Jul, 28, 2026

52 people who take Lenalidomide and Jardiance together, and have interactions are studied.

Lenalidomide and Jardiance drug interactions.

What are the common drug interactions of Lenalidomide and Jardiance, by gender? *:

female:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Lactic acidosis (low ph in body tissues)
  3. Abdominal pain upper
  4. Anaemia (lack of blood)
  5. Asthenia (weakness)
  6. C-reactive protein increased
  7. Cardiac failure
  8. Chills (felling of cold)
  9. Cough
  10. Lower respiratory tract infection

male:

  1. Blood pressure increased
  2. Feeling hot
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Arthralgia (joint pain)
  5. Arthropathy
  6. Oedematous pancreatitis (interstitial inflammation and swelling of pancreas)
  7. Pneumonia
  8. Blood glucose increased
  9. Blood magnesium decreased
  10. Colonoscopy

What are the common drug interactions of Lenalidomide and Jardiance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Colonoscopy

40-49:

  1. Blood pressure increased
  2. Feeling hot
  3. Head discomfort
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Lactic acidosis (low ph in body tissues)

60+:

  1. C-reactive protein increased
  2. Pneumonia
  3. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  4. Diarrhoea
  5. Hospitalisation
  6. Oedematous pancreatitis (interstitial inflammation and swelling of pancreas)
  7. Blood glucose increased
  8. Blood magnesium decreased
  9. Colon cancer
  10. Death

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 36 people, 69.23%
  2. High Blood Pressure: 18 people, 34.62%
  3. Type 2 Diabetes: 14 people, 26.92%
  4. Pain: 13 people, 25.00%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 21.15%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 19.23%
  7. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 7.69%
  8. Primary Amyloidosis (disease that occurs when substances called amyloid proteins build up in your organs): 3 people, 5.77%
  9. High Blood Cholesterol: 3 people, 5.77%
  10. Amyloidosis (a tumour within which amyloid is produced): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Lenalidomide and Jardiance?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lenalidomide and Jardiance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lenalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Jardiance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lenalidomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Jardiance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lenalidomide and empagliflozin (the active ingredients of Lenalidomide and Jardiance, respectively), and Lenalidomide and Jardiance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: