Lenalidomide and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lenalidomide (lenalidomide) and Seroquel (quetiapine fumarate). Common drug interactions include mucosal inflammation among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Lenalidomide and Seroquel. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.



On Jul, 16, 2026

53 people who take Lenalidomide and Seroquel together, and have interactions are studied.

Lenalidomide and Seroquel drug interactions.

What are the common drug interactions of Lenalidomide and Seroquel, by gender? *:

female:

  1. Mucosal inflammation (infection of mucous membrane)
  2. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  3. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  4. Neuropathy peripheral (surface nerve damage)
  5. Oral disorder (mouth disease)
  6. Osteolysis (dissolution of bone)
  7. Osteonecrosis of jaw (death of bone of jaw)
  8. Pain in extremity
  9. Pain in jaw
  10. Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)

male:

  1. Fall
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Anaemia (lack of blood)
  4. Pneumonia
  5. Angina pectoris (chest pain due to ischemia of the heart muscle)
  6. Plasma cell myeloma (cancer that begins in plasma cells)
  7. Platelet count decreased
  8. Dementia (madness)
  9. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  10. Hypokalaemia (low potassium)

What are the common drug interactions of Lenalidomide and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Chest pain
  2. Platelet count decreased
  3. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  4. Thrombocytopenia (decrease of platelets in blood)

30-39:

n/a

40-49:

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  2. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

50-59:

  1. Constipation
  2. Decreased appetite
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Femur fracture
  6. Fungal infection
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Mouth haemorrhage (bleeding from mouth)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Pneumonia

60+:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Fall
  3. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  4. Dehydration (dryness resulting from the removal of water)
  5. Electrocardiogram qt prolonged
  6. Gastroenteritis (inflammation of stomach and intestine)
  7. Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
  8. Troponin i increased
  9. Ventricular extrasystoles (premature cardiac contraction)
  10. Anaemia (lack of blood)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 42 people, 79.25%
  2. Depression: 7 people, 13.21%
  3. High Blood Pressure: 5 people, 9.43%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 5.66%
  5. Nausea (feeling of having an urge to vomit): 3 people, 5.66%
  6. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 3 people, 5.66%
  7. Diabetes: 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lenalidomide and Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lenalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lenalidomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Seroquel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lenalidomide and quetiapine fumarate (the active ingredients of Lenalidomide and Seroquel, respectively), and Lenalidomide and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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