Letrozole and Alphagan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Letrozole (letrozole) and Alphagan (brimonidine tartrate). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Letrozole and Alphagan. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Letrozole?

Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

On Jul, 14, 2026

26 people who take Letrozole and Alphagan together, and have interactions are studied.

Letrozole and Alphagan drug interactions.

What are the common drug interactions of Letrozole and Alphagan, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Dysuria (painful or difficult urination)
Headache (pain in head)
Rash
Abdominal distension
Amaurosis fugax (painless transient monocular visual loss)
Anxiety
Asthenia (weakness)
Atrophic vulvovaginitis (inflammation of the vulva)

male:

n/a

What are the common drug interactions of Letrozole and Alphagan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Back disorder
Benign neoplasm of adrenal gland (benign (non-cancerous) tumours of the adrenal gland)
Blindness
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bruxism (habitual grinding of the teeth, typically during sleep)
Cataract (clouding of the lens inside the eye)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Constipation

60+:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pain
Vomiting
White blood cell count decreased
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Contusion (a type of hematoma of tissue in which capillaries)
Cough

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 10 people, 38.46%
Pain: 8 people, 30.77%
Constipation: 5 people, 19.23%
Urinary Tract Infection: 4 people, 15.38%
Diarrhea: 4 people, 15.38%
High Blood Cholesterol: 4 people, 15.38%
Back Pain: 4 people, 15.38%
Rashes (redness): 3 people, 11.54%
Rickets (softening of bones): 3 people, 11.54%
Blood Thyroid Stimulating Hormone Decreased: 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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