Dilaudid and Aptyalism - a phase IV clinical study of FDA data

Summary:

Aptyalism is reported as a side effect among people who take Dilaudid (hydromorphone hydrochloride), especially for people who are female, 50-59 old, also take Zofran, and have Osteoporosis.

The phase IV clinical study analyzes which people have Aptyalism when taking Dilaudid. It is created by eHealthMe based on reports of 95,518 people who have side effects when taking Dilaudid from the FDA, and is updated regularly.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

What is Aptyalism?

Aptyalism (deficiency or absence of saliva) is found to be associated with 213 drugs and 391 conditions by eHealthMe. Check the latest studies of Aptyalism.

On Jul, 14, 2026

95,518 people reported to have side effects when taking Dilaudid.
Among them, 29 people (0.03%) have Aptyalism.

Among these 29 people:

What is the gender of people who have Aptyalism when taking Dilaudid? *

female: 100 %
male: 0.0 %

What is the age of people who have Aptyalism when taking Dilaudid? *

What are other drugs people take besides Dilaudid? *

What are other side effects people have besides Aptyalism? *

Pneumonia: 29 people, 100.00%
Bone Pain: 28 people, 96.55%
Tricuspid Valve Incompetence (inefficient heart valve): 28 people, 96.55%
Bone Fragmentation: 28 people, 96.55%
Bone Disorder: 28 people, 96.55%
Asthma: 28 people, 96.55%
Appendicitis (inflammation of the appendix): 28 people, 96.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 28 people, 96.55%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 27 people, 93.10%
Tympanic Membrane Disorder (disease of ear drum): 27 people, 93.10%

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 27 people, 93.10%
Osteoporosis (bones weak and more likely to break): 27 people, 93.10%
Thrombocytopenia (decrease of platelets in blood): 11 people, 37.93%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 1 person, 3.45%
Paraneoplastic Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 3.45%
Myositis (inflammation of the muscles): 1 person, 3.45%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Dilaudid and have Aptyalism?

- Check whether Aptyalism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilaudid:

Dilaudid (96,466 reports)

Aptyalism treatments and more:

Aptyalism (1,482 reports)

Browse all side effects of Dilaudid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aptyalism:

Aptyalism (213 drugs)

Browse all the conditions that are associated with Aptyalism:

Aptyalism (391 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride (the active ingredients of Dilaudid) and Dilaudid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.