Leukine and Lorazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Leukine (sargramostim) and Lorazepam (lorazepam). Common drug interactions include nausea among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Leukine and Lorazepam. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.
What is Leukine?
Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.
What is Lorazepam?
Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.
79 people who take Leukine and Lorazepam together, and have interactions are studied.

What are the common drug interactions of Leukine and Lorazepam, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Chest pain
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
- Transaminases increased
- Cholecystitis (infection of gallbladder)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Haemorrhage intracranial (bleeding within the skull)
male:
- Abdominal pain
- Nausea (feeling of having an urge to vomit)
- Bone disorder
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Constipation
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Dizziness
- Erectile dysfunction
- Hypercholesterolaemia (high levels of cholesterol in the blood)
- Osteomyelitis (infection of bone)
What are the common drug interactions of Leukine and Lorazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
- Hypokalaemia (low potassium)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Pain
- Pruritus (severe itching of the skin)
- Pyrexia (fever)
- Weight increased
- Hospitalisation
10-19:
- Caecitis (inflammation of the cecum)
- Depressed level of consciousness
- Escherichia infection (bacterial infection by escherichia coli)
- Febrile neutropenia (fever with reduced white blood cells)
- Hypoxia (low oxygen in tissues)
- Pneumonia
- Clostridial infection (infectious conditions by clostridium bacteria)
- Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
- Abdominal distension
- Abdominal pain upper
20-29:
- Malaise (a feeling of general discomfort or uneasiness)
- Weight decreased
30-39:
- Unevaluable reaction
40-49:
- Nausea (feeling of having an urge to vomit)
- Abdominal pain
- Oedema peripheral (superficial swelling)
- Respiratory distress (difficulty in breathing)
- Application site reaction
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Blood creatinine increased
- Cardiac ventricular disorder (ventricular dysfunction of heart)
- Conduction disorder (serious disorder of the heart not responses proper to impulses)
- Constipation
50-59:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Pain
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Abdominal pain
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Blood oestrogen increased
60+:
- Abdominal pain
- Nausea (feeling of having an urge to vomit)
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Dizziness
- Erectile dysfunction
- Hypercholesterolaemia (high levels of cholesterol in the blood)
- Osteomyelitis (infection of bone)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain
- Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
What are the existing conditions these people have? *
- Pain: 18 people, 22.78%
- Nausea (feeling of having an urge to vomit): 18 people, 22.78%
- Insomnia (sleeplessness): 18 people, 22.78%
- Malignant Melanoma (skin cancer rises from melancytes): 17 people, 21.52%
- High Blood Cholesterol: 16 people, 20.25%
- Prostate Cancer: 14 people, 17.72%
- Osteoporosis (bones weak and more likely to break): 10 people, 12.66%
- Abdominal Pain: 9 people, 11.39%
- Gynecomastia (enlargement of the gland tissue of the male breast): 7 people, 8.86%
- Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 7 people, 8.86%
* Approximation only. Some reports may have incomplete information.
Do you take Leukine and Lorazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Leukine and Lorazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Leukine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lorazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Leukine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lorazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sargramostim and lorazepam (the active ingredients of Leukine and Lorazepam, respectively), and Leukine and Lorazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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