Levaquin and Combivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Combivir (lamivudine; zidovudine). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Combivir. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

On Jul, 16, 2026

59 people who take Levaquin and Combivir together, and have interactions are studied.

Levaquin and Combivir drug interactions.

What are the common drug interactions of Levaquin and Combivir, by gender? *:

female:

Chronic kidney disease
Osteopenia (a condition where bone mineral density is lower than normal)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Back pain
Bone density decreased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Gait disturbance
Pancreatitis acute (sudden inflammation of pancreas)

male:

Chronic kidney disease
Emotional distress
Anaemia (lack of blood)
Dyspnoea (difficult or laboured respiration)
Renal impairment (severely reduced kidney function)
Decreased activity
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Fatigue (feeling of tiredness)
Quality of life decreased
Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Levaquin and Combivir, by age (0-1 to 60+)? *:

0-1:

Drug screen false positive

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Emotional distress
Pain
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Death
Decreased activity
Fear
Impaired work ability

30-39:

Pain
Bone density decreased
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fatigue (feeling of tiredness)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

40-49:

Chronic kidney disease
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Neuropathy peripheral (surface nerve damage)
Renal impairment (severely reduced kidney function)
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Renal failure (kidney dysfunction)
Bone pain

50-59:

Drug resistance (reduction in effectiveness of a drug)
Dyslipidaemia (abnormal amount of lipids)
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphemia (stammering or stuttering)
Emotional disorder
Excessive eye blinking (excessive blinking is dry eyes)
Exercise tolerance decreased
Face oedema (swelling of face)
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Osteopenia (a condition where bone mineral density is lower than normal)
Ankle fracture
Bone density decreased
Cystitis (inflammation of the wall of the bladder)
Dysstasia (difficulty in standing)
Mobility decreased (ability to move is reduced)
Renal impairment (severely reduced kidney function)
Tooth loss

What are the existing conditions these people have? *

Hiv Infection: 42 people, 71.19%
Diabetes: 3 people, 5.08%
Depression: 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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