Levaquin and Doryx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Doryx (doxycycline hyclate). Common drug interactions include chronic kidney disease among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Doryx. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Doryx?

Doryx has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 901 Doryx users. Check the latest studies of Doryx.

On Jul, 21, 2026

20 people who take Levaquin and Doryx together, and have interactions are studied.

What are the common drug interactions of Levaquin and Doryx, by gender? *:

female:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Drug hypersensitivity

male:

Cellulitis (infection under the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Actinic keratosis (skin disease due to sun exposure)
Adenoma benign (non-cancerous tumour -secreting)
Anal abscess
Anal fissure
Anal fistula
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

What are the common drug interactions of Levaquin and Doryx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bone atrophy (decrease in bone mass)
Bone density decreased
Bone disorder
Bone loss
Bone neoplasm (tumour of bone)
Bone pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac murmur (an heart sound in valve abnormality)
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cellulitis (infection under the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Chronic kidney disease
Dyspepsia (indigestion)
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrioventricular block first degree (heart block first degree)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bladder obstruction

What are the existing conditions these people have? *

Stress And Anxiety: 10 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 40.00%
Depression: 8 people, 40.00%
Pain: 7 people, 35.00%
Groin Infection (infection in groin): 6 people, 30.00%
Enlarged Prostate: 6 people, 30.00%
Diarrhea: 6 people, 30.00%
Insomnia (sleeplessness): 6 people, 30.00%
Joint Pain: 6 people, 30.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 30.00%

* Approximation only. Some reports may have incomplete information.

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