Levaquin and Floxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Floxin (ofloxacin). Common drug interactions include dental caries among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Floxin. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

On Jul, 09, 2026

80 people who take Levaquin and Floxin together, and have interactions are studied.

What are the common drug interactions of Levaquin and Floxin, by gender? *:

female:

Dental caries
Hypophagia (reduced food intake)
Foot fracture
Metastases to spine (cancer spreads to spine)
Oedema peripheral (superficial swelling)
Osteonecrosis of jaw (death of bone of jaw)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Neuropathy peripheral (surface nerve damage)
Asthenia (weakness)

male:

Pain
Cardiac failure congestive
Fall
Hypokalaemia (low potassium)
Palpitations (feelings or sensations that your heart is pounding or racing)
Syncope (loss of consciousness with an inability to maintain postural tone)
Depression
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Levaquin and Floxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Back pain
Myalgia (muscle pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dyspnoea (difficult or laboured respiration)
Anxiety
Asthenia (weakness)
Burning sensation
Depression
Emotional distress
Injury

40-49:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Pain
Anxiety
Asthenia (weakness)
Depression
Hyperglycaemia (high blood sugar)
Type 2 diabetes mellitus
Abdominal discomfort
Abdominal distension
Arthropathy

50-59:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Death
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)
Hepatic neoplasm malignant (liver cancer)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Liver fatty (fat deposition of liver)
Metastases to large intestine (cancer spreads to large intestine)
Nephrogenic anaemia (anaemia due to kidney disease)

60+:

Pain
Cardiomegaly (increased size of heart than normal)
Injury
Pain in extremity
Anxiety
Balance disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypophagia (reduced food intake)
Interstitial lung disease

What are the existing conditions these people have? *

Pain: 6 people, 7.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.50%
Stress And Anxiety: 5 people, 6.25%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 6.25%
Depression: 5 people, 6.25%
Constipation: 5 people, 6.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 6.25%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 5.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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