Levaquin and Jardiance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Jardiance (empagliflozin). Common drug interactions include depression among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Jardiance. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,459 Jardiance users. Check the latest studies of Jardiance.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

43 people who take Levaquin and Jardiance together, and have interactions are studied.

Levaquin and Jardiance drug interactions.

What are the common drug interactions of Levaquin and Jardiance, by gender? *:

female:

Depression
Dermal cyst
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Extravasation (leakage of a fluid)
Gastrointestinal bacterial infection (infection of the stomach and intestines caused by bacteria)
Hypersensitivity
Hypoacusis (loss of hearing)
Immune system disorder
Influenza

male:

Asthenia (weakness)
Diarrhoea
Balance disorder
Blood triglycerides increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Cystitis (inflammation of the wall of the bladder)
Death
Depressed level of consciousness
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Levaquin and Jardiance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Sepsis (a severe blood infection that can lead to organ failure and death)
Renal failure (kidney dysfunction)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Abscess (pus)
Abscess limb (limb infection)
Alopecia (absence of hair from areas of the body)
Anal abscess
Cellulitis (infection under the skin)
Chronic kidney disease
Drug eruption (adverse drug reaction of the skin)

50-59:

Rash
Scar
Skin exfoliation (removal of the oldest dead skin cells)
Sputum discoloured
Streptococcal sepsis (whole body inflammation by streptococcal)
Thrombocytosis
Ulcer
Urinary tract infection
Urinary tract obstruction
White blood cell count increased

60+:

Asthenia (weakness)
General physical health deterioration (weak health status)
Depressed level of consciousness
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Erectile dysfunction
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Faecaloma (hard mass of fecal matter)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Influenza

What are the existing conditions these people have? *

Type 2 Diabetes: 13 people, 30.23%
Pain: 6 people, 13.95%
Immunodeficiency Common Variable: 6 people, 13.95%
Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 9.30%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 9.30%
Pneumonia: 4 people, 9.30%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.30%
Diarrhea: 4 people, 9.30%
Diabetes: 4 people, 9.30%
Nausea And Vomiting: 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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