Levaquin and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Naltrexone (naltrexone). Common drug interactions include alopecia among females and carpal tunnel syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Naltrexone. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,833 Naltrexone users. Check the latest studies of Naltrexone.



On Jul, 16, 2026

14 people who take Levaquin and Naltrexone together, and have interactions are studied.

Levaquin and Naltrexone drug interactions.

What are the common drug interactions of Levaquin and Naltrexone, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Back pain
  3. Drug ineffective
  4. Kidney infection
  5. Post procedural complication
  6. Chronic fatigue syndrome (disorder that causes extreme fatigue)
  7. Dizziness
  8. Hypersensitivity
  9. Mastoiditis (infection of mastoid bone)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  2. Deep brain stimulation
  3. Upper respiratory tract infection
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Hypotension (abnormally low blood pressure)
  6. Increased upper airway secretion
  7. Joint injury
  8. Joint swelling
  9. Lower respiratory tract infection
  10. Mucosal discolouration (change in colour of mucosal membrane)

What are the common drug interactions of Levaquin and Naltrexone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Acne (skin problems that cause pimples)
  3. Blood cholesterol increased
  4. Blood pressure decreased
  5. Diarrhoea
  6. Dizziness
  7. Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
  8. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  9. Mastoiditis (infection of mastoid bone)
  10. Nausea (feeling of having an urge to vomit)

40-49:

n/a

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Back pain
  3. Drug ineffective
  4. Post procedural complication
  5. Hypersensitivity
  6. Scar
  7. Bacterial infection
  8. Kidney infection

60+:

  1. Chronic fatigue syndrome (disorder that causes extreme fatigue)
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Hypotension (abnormally low blood pressure)
  4. Increased upper airway secretion
  5. Insomnia (sleeplessness)
  6. Joint injury
  7. Joint swelling
  8. Lower respiratory tract infection
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Mucosal discolouration (change in colour of mucosal membrane)

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 50.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 42.86%
  3. Immunodeficiency Common Variable: 4 people, 28.57%
  4. Sleep Disorder: 2 people, 14.29%
  5. Drowsiness: 2 people, 14.29%
  6. Urinary Tract Infection: 1 person, 7.14%
  7. Headache (pain in head): 1 person, 7.14%
  8. Bone Disorder: 1 person, 7.14%
  9. Dry Eyes (lack of adequate tears): 1 person, 7.14%
  10. Enlarged Prostate: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Levaquin and Naltrexone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levaquin and Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Naltrexone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levaquin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naltrexone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levofloxacin and naltrexone (the active ingredients of Levaquin and Naltrexone, respectively), and Levaquin and Naltrexone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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