Levaquin and Rexulti drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Rexulti (brexpiprazole). Common drug interactions include drug hypersensitivity among females and blood glucose decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Rexulti. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Rexulti?

Rexulti has active ingredients of brexpiprazole. It is often used in major depression. eHealthMe is studying from 13,394 Rexulti users. Check the latest studies of Rexulti.

On Jul, 13, 2026

18 people who take Levaquin and Rexulti together, and have interactions are studied.

What are the common drug interactions of Levaquin and Rexulti, by gender? *:

female:

Drug hypersensitivity
Migraine (headache)
Arthropathy
Nasal septum deviation (deviated nasal septum)
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Toothache (tooth pain)
Trigger finger
Suicidal ideation
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

male:

Blood glucose decreased
Blood pressure decreased
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Dizziness
Drug hypersensitivity
Fall
Gait disturbance

What are the common drug interactions of Levaquin and Rexulti, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Cardiomegaly (increased size of heart than normal)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Pleural effusion (water on the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Suicidal ideation

40-49:

Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

50-59:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Knee arthroplasty
Neuralgia (pain in one or more nerves)
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
Abdominal distension
Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anorectal disorder
Anxiety
Blood glucose increased

60+:

Drug hypersensitivity
Blood glucose decreased
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)
Blood pressure decreased
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Dizziness
Fall
Gait disturbance

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 44.44%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 16.67%
Thyroid Diseases: 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.56%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 1 person, 5.56%
Depression: 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%
Gout (uric acid crystals building up in the body): 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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