Levaquin and Tadalafil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Tadalafil (tadalafil). Common drug interactions include pneumonia bacterial among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Tadalafil. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Tadalafil?

Tadalafil has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 25,549 Tadalafil users. Check the latest studies of Tadalafil.



On Jul, 31, 2026

19 people who take Levaquin and Tadalafil together, and have interactions are studied.

Levaquin and Tadalafil drug interactions.

What are the common drug interactions of Levaquin and Tadalafil, by gender? *:

female:

  1. Pneumonia bacterial (pneumonia associated with bacterial infection)
  2. Dyspnoea (difficult or laboured respiration)
  3. Fall
  4. Alanine aminotransferase increased
  5. Ankle fracture
  6. Arthralgia (joint pain)
  7. Asthma
  8. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  9. Bradycardia (abnormally slow heart action)
  10. Chest discomfort

male:

  1. Chronic kidney disease
  2. Gait disturbance
  3. Mobility decreased (ability to move is reduced)
  4. Pain
  5. Renal impairment (severely reduced kidney function)
  6. Urinary tract disorder
  7. Acute respiratory failure
  8. Back pain
  9. Balance disorder
  10. Bladder disorder

What are the common drug interactions of Levaquin and Tadalafil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Drug hypersensitivity
  2. Vomiting

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Hepatic enzyme increased
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Renal failure (kidney dysfunction)
  5. Balance disorder
  6. Death
  7. Depression
  8. Dizziness
  9. Drug abuse
  10. Drug dependence

60+:

  1. Pneumonia bacterial (pneumonia associated with bacterial infection)
  2. Dyspnoea (difficult or laboured respiration)
  3. Chest discomfort
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Cough
  6. Dizziness
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Nausea (feeling of having an urge to vomit)
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 36.84%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 31.58%
  3. High Blood Pressure: 6 people, 31.58%
  4. Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 26.32%
  5. High Blood Cholesterol: 4 people, 21.05%
  6. Pain: 4 people, 21.05%
  7. Dehydration (dryness resulting from the removal of water): 2 people, 10.53%
  8. Hiv Infection: 2 people, 10.53%
  9. Diabetes: 2 people, 10.53%
  10. Infection: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levaquin and Tadalafil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levaquin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tadalafil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levaquin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tadalafil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levofloxacin and tadalafil (the active ingredients of Levaquin and Tadalafil, respectively), and Levaquin and Tadalafil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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