Levaquin and Vascepa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Vascepa (icosapent ethyl). Common drug interactions include bronchitis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Vascepa. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

29 people who take Levaquin and Vascepa together, and have interactions are studied.

What are the common drug interactions of Levaquin and Vascepa, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Arthralgia (joint pain)
Bronchitis viral (inflammation of the mucous membrane in the bronchial tubes due to infection with streptococcus pneumoniae)
Cellulitis (infection under the skin)
Chronic kidney disease
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dyspnoea (difficult or laboured respiration)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Fatigue (feeling of tiredness)

male:

Chronic kidney disease
Fatigue (feeling of tiredness)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Diarrhoea
Ear discomfort
Ear infection
Gait disturbance
Gastric disorder (disease of stomach)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the common drug interactions of Levaquin and Vascepa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abscess limb (limb infection)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Orchitis (inflammation of the testes)
Scrotal abscess (pus in scrotum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection

30-39:

n/a

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Influenza
Renal injury (kidney injury)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchitis viral (inflammation of the mucous membrane in the bronchial tubes due to infection with streptococcus pneumoniae)
Cellulitis (infection under the skin)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dyspnoea (difficult or laboured respiration)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)

60+:

Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Gait disturbance
Gastric disorder (disease of stomach)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Pain in extremity
Platelet count decreased
Restless legs syndrome (a powerful urge to move your legs)
Rash

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 31.03%
Pain: 8 people, 27.59%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 27.59%
High Blood Pressure: 6 people, 20.69%
Infection: 6 people, 20.69%
Type 2 Diabetes: 5 people, 17.24%
Hypersensitivity: 4 people, 13.79%
Stress And Anxiety: 4 people, 13.79%
Depression: 4 people, 13.79%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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