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Levetiracetam and Sandostatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levetiracetam (levetiracetam) and Sandostatin (octreotide acetate). Common drug interactions include injection site bruising among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Levetiracetam and Sandostatin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Levetiracetam?

Levetiracetam has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 75,292 Levetiracetam users. Check the latest studies of Levetiracetam.

What is Sandostatin?

Sandostatin has active ingredients of octreotide acetate. It is often used in acromegaly. eHealthMe is studying from 46,793 Sandostatin users. Check the latest studies of Sandostatin.



On Jul, 21, 2026

41 people who take Levetiracetam and Sandostatin together, and have interactions are studied.

Levetiracetam and Sandostatin drug interactions.

What are the common drug interactions of Levetiracetam and Sandostatin, by gender? *:

female:

  1. Injection site bruising
  2. Injection site swelling
  3. Joint swelling
  4. Limb discomfort (discomfort in leg)
  5. Lipoma (a growth of fatty tissue that slowly develops just under your skin)
  6. Nephrolithiasis (calculi in the kidneys)
  7. Overweight
  8. Weight loss poor
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Cough
  3. Decreased appetite
  4. Diarrhoea
  5. Drug effect decreased
  6. Heart rate decreased
  7. Hot flush (sudden feelings of heat)
  8. Intestinal obstruction
  9. Muscular weakness (muscle weakness)
  10. Pain

What are the common drug interactions of Levetiracetam and Sandostatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cough
  2. Nausea (feeling of having an urge to vomit)
  3. Abdominal distension
  4. Abdominal infection
  5. Abdominal pain
  6. Abdominal pain lower
  7. Blood pressure decreased
  8. Blood pressure systolic increased
  9. Decreased appetite
  10. Diarrhoea

30-39:

  1. Skin wound
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Vomiting
  4. Pneumonia
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Abdominal pain
  7. Confusional state
  8. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  9. Nausea (feeling of having an urge to vomit)
  10. Right ventricular failure (right half of the heart fails to work)

40-49:

  1. Injection site haemorrhage (bleeding from injection site)
  2. Abdominal pain
  3. Abdominal pain lower
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Blood pressure increased
  7. Blood pressure systolic increased
  8. Blood sodium decreased
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Contusion (a type of hematoma of tissue in which capillaries)

50-59:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Anaemia (lack of blood)
  3. Brain contusion (a form of traumatic brain injury)
  4. Cerebral haemorrhage (bleeding within the brain)
  5. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  6. Irritability
  7. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  8. Rib fracture
  9. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  10. Arthralgia (joint pain)

60+:

  1. Pyrexia (fever)
  2. Abnormal faeces (abnormal stool)
  3. Injection site haemorrhage (bleeding from injection site)
  4. Injection site pain
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Muscle rigidity (muscle stiffness)
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  8. Skin hypertrophy (skin cells enlarges)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

  1. Thyroid Diseases: 6 people, 14.63%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 14.63%
  3. Pituitary Tumor: 6 people, 14.63%
  4. Blood Prolactin Abnormal: 6 people, 14.63%
  5. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 9.76%
  6. Neuroendocrine Tumor: 4 people, 9.76%
  7. Diarrhea: 4 people, 9.76%
  8. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 4 people, 9.76%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levetiracetam and Sandostatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levetiracetam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sandostatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levetiracetam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sandostatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levetiracetam and octreotide acetate (the active ingredients of Levetiracetam and Sandostatin, respectively), and Levetiracetam and Sandostatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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