Levofloxacin and Clopidogrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levofloxacin (levofloxacin; sodium chloride) and Clopidogrel (clopidogrel). Common drug interactions include pleural effusion among females and renal failure acute among males.

The phase IV clinical study analyzes what interactions people have when they take Levofloxacin and Clopidogrel. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Levofloxacin?

Levofloxacin has active ingredients of levofloxacin; sodium chloride. It is often used in sinusitis. eHealthMe is studying from 16,335 Levofloxacin users. Check the latest studies of Levofloxacin.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

76 people who take Levofloxacin and Clopidogrel together, and have interactions are studied.

Levofloxacin and Clopidogrel drug interactions.

What are the common drug interactions of Levofloxacin and Clopidogrel, by gender? *:

female:

Pleural effusion (water on the lungs)
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Asthenia (weakness)
Coagulopathy (blood's ability to clot is impaired)
Contusion (a type of hematoma of tissue in which capillaries)
Blood thyroid stimulating hormone increased
Depersonalisation
Depressed mood
Derealisation

male:

Renal failure acute (rapid kidney dysfunction)
Anaemia (lack of blood)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Respiratory failure (inadequate gas exchange by the respiratory system)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Unresponsive to stimuli
Coagulopathy (blood's ability to clot is impaired)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

What are the common drug interactions of Levofloxacin and Clopidogrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Peritoneal dialysis complication
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Death

30-39:

Renal failure acute (rapid kidney dysfunction)
Heparin-induced thrombocytopenia
Skin necrosis (skin damage)

40-49:

n/a

50-59:

Mood disorder due to a general medical condition
Pleural effusion (water on the lungs)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Acute myocardial infarction (acute heart attack)
Cardiac failure acute
Cardiogenic shock (inadequate circulation of blood)
Hypotension (abnormally low blood pressure)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)

60+:

Asthenia (weakness)
Blood creatinine increased
Drug ineffective
Localised oedema (fluid retention in a particular part of the body)
Loss of consciousness
Melaena (the passage of black, tarry stools)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Oedema peripheral (superficial swelling)
Pruritus (severe itching of the skin)
Pulse absent

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 13.16%
Pain: 7 people, 9.21%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 7 people, 9.21%
Fever: 6 people, 7.89%
Stress And Anxiety: 5 people, 6.58%
Cardiac Failure: 5 people, 6.58%
Urinary Tract Infection: 4 people, 5.26%
Febrile Infection (infection with temperature rise): 4 people, 5.26%
Diabetes: 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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