Levofloxacin and Zoloft drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levofloxacin (levofloxacin; sodium chloride) and Zoloft (sertraline hydrochloride). Common drug interactions include dyspnoea among females and failure to thrive among males.

The phase IV clinical study analyzes what interactions people have when they take Levofloxacin and Zoloft. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Levofloxacin?

Levofloxacin has active ingredients of levofloxacin; sodium chloride. It is often used in sinusitis. eHealthMe is studying from 16,335 Levofloxacin users. Check the latest studies of Levofloxacin.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

On Jul, 10, 2026

98 people who take Levofloxacin and Zoloft together, and have interactions are studied.

Levofloxacin and Zoloft drug interactions.

What are the common drug interactions of Levofloxacin and Zoloft, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Vision blurred
Vomiting
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Arthralgia (joint pain)
Constipation
Nausea (feeling of having an urge to vomit)
Neuralgia (pain in one or more nerves)
Oedema peripheral (superficial swelling)
Pain in extremity

male:

Failure to thrive (inadequate weight gain and physical growth in children)
Diarrhoea
Dizziness
Headache (pain in head)
Arthralgia (joint pain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Ataxia (loss of full control of bodily movements)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Death
Dizziness (excl vertigo)

What are the common drug interactions of Levofloxacin and Zoloft, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Biliary dilatation
Bone disorder
Bone pain
Calcium deficiency (lack of calcium)
Cataract (clouding of the lens inside the eye)
Cholangitis (infection of the bile duct)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

30-39:

Anal atresia (anus is either not present or it is in the wrong place)
Constipation
Crying
Failure to thrive (inadequate weight gain and physical growth in children)
Female genital tract fistula (passage in genital tract of female)
Flatulence (flatus expelled through the anus)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Intestinal atresia (malformation where there is a narrowing or absence of a portion of the intestine)
Deafness
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

40-49:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Acute respiratory distress syndrome
Pulmonary arterial pressure increased
Abdominal pain
Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Arthralgia (joint pain)
Asthma
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)

50-59:

Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Impaired healing
Inflammation
Jaw disorder (jaw disease)
Livedo reticularis (a lace-like purplish discoloration of the skin)
Mass
Neuralgia (pain in one or more nerves)
Neuropathy (damage to nerves)
Oral soft tissue disorder (oral soft tissue disease)
Osteitis (a general term for inflammation of bone)

60+:

Diarrhoea
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
General physical health deterioration (weak health status)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Arrhythmia (irregular heartbeat)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dizziness
Dyspnoea (difficult or laboured respiration)
Failure to thrive (inadequate weight gain and physical growth in children)
International normalised ratio increased

What are the existing conditions these people have? *

Stress And Anxiety: 10 people, 10.20%
High Blood Pressure: 9 people, 9.18%
High Blood Cholesterol: 7 people, 7.14%
Pneumonia: 6 people, 6.12%
Pain: 5 people, 5.10%
Asthma: 5 people, 5.10%

* Approximation only. Some reports may have incomplete information.

Do you take Levofloxacin and Zoloft?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously